Protein Alignment CG6927 and Gabra3

DIOPT Version :9

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001344745.1
• Gene: Gabra3 / 14396
• MGIID: 95615
• Length: 523
• Species: Mus musculus
• Alignment Length: 565
• Identity: 129/565 - (22%)
• Similarity: 219/565 - (38%)
• Gaps: 151/565 - (26%)

  Fly     5 LIISILLNCLYASASALDE------------------DCPTLDDGDSLS-QTQLLDRLTHGCRYD 50
            |:||||........|...|                  |.|. |..|::: .|::||||..|  ||
Mouse    49 LLISILPGTTSQGESRRQEPGDFVKQDIGGLSPKHAPDIPD-DSTDNITIFTRILDRLLDG--YD 110

  Fly    51 RLERP-----ITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSP 110
            ...||     :|..:|      |:|:.::    ..:...|:::.|....:..:.|.||.|.  .|
Mouse   111 NRLRPGLGDAVTEVKT------DIYVTSF----GPVSDTDMEYTIDVFFRQTWHDERLKFD--GP 163

  Fly   111 KRRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNL 175
            .:..|:  ...|.:.:|.|..|..|.:.|....:|..:.|..:..:||::.:.|:.....|.::|
Mouse   164 MKILPL--NNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHL 226

  Fly   176 KKFPFDEQHCSTVLESWMYNTSELVLHW----EQKRPITYDGALHLTEFVLQRSWSNETVINADL 236
            :.||.|...|.....|:.|..:|::..|    .:...:..||: .|.::.|........:|.:.
Mouse   227 EDFPMDVHACPLKFGSYAYTKAEVIYSWTLGKNKSVEVAQDGS-RLNQYDLLGHVVGTEIIRSS- 289

  Fly   237 SDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTL 301
                    .|.|..::...||.|.:|::::..:||.::.|.:|.|||||..:..|.|...|.:|:
Mouse   290 --------TGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 346

  Fly   302 LTFITLASAQGKTLPKVSYIKVSEVWFLG-CTIFIFGSMVEFAFVNTI------WRRKK------ 353
            ||..||:.:...:||||:|....: ||:. |..|:|.:::|||.||..      |..||
Mouse   347 LTMTTLSISARNSLPKVAYATAMD-WFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVPEALE 410

  Fly   354 ------SVPVKKLNSKHILKSTLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVN 412
                  :.|.||..:.:|:.:|...||      |:...||
Mouse   411 MKKKTPAAPTKKNTTFNIVGTTYPINL------AKDTEFS------------------------- 444

  Fly   413 LPITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGH 477
               |..|.........|...:......:|:.                 |.::|.|.|:.::
Mouse   445 ---TISKSAAAPSASSTPTAIASPKATYVQD-----------------SPAETKTYNSVSK---- 485

  Fly   478 QEEIDLSGWTTLTPQEIAMWIDSRARFVFPLSFLVFNLFFW-TFV 521
                                :|..:|.:||:.|.:|||.:| |:|
Mouse   486 --------------------VDKISRIIFPVLFAIFNLVYWATYV 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:273305	127/562 (23%)
		Neur_chan_LBD	36..259	CDD:280998	52/231 (23%)
		Neur_chan_memb	270..518	CDD:280999	61/266 (23%)
Gabra3	NP_001344745.1	Neur_chan_LBD	100..509	CDD:332142	115/510 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900