Protein Alignment CG6927 and Gabra4

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_542154.3
• Gene: Gabra4 / 140675
• RGDID: 621670
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 141/591 - (23%)
• Similarity: 234/591 - (39%)
• Gaps: 145/591 - (24%)

  Fly     5 LIISILLNCLYASASALDED---CPTLDDGDSLSQTQLLDRLTHGCRYDRLER-----PITYSET 61
            |.:..|..||..|.....:|   ||.       :.|::||.|..|  ||...|     |:|..:|
  Rat    21 LHVLCLATCLNESPGQNSKDEKLCPE-------NFTRILDSLLDG--YDNRLRPGFGGPVTEVKT 76

  Fly    62 GQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRRQPILGEEHLR--- 123
                  |:|:.::    ..:...::::.:....:..::|.||.:..       ||   |.||
  Rat    77 ------DIYVTSF----GPVSDVEMEYTMDVFFRQTWIDKRLKYDG-------PI---EILRLNN 121

  Fly   124 ---NSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQHC 185
               ..:|.|..|..|.:.|....:|..:.|..|..:||::.:.|:..:..|.:.|..||.|...|
  Rat   122 MMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHAC 186

  Fly   186 STVLESWMYNTSELVLHW------------EQKRPITYDGALHLTEFVLQRSWSNETVINADLSD 238
            .....|:.|..||::..|            |....:.||        ::.::.|:||:
  Rat   187 PLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYD--------LIGQTVSSETI------- 236

  Fly   239 LRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLT 303
               .:..|.|..::...||.|.:|::::..::|.::.|.:|.||||:..:..|.|...|.:|:||
  Rat   237 ---KSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLT 298

  Fly   304 FITLASAQGKTLPKVSYIKVSEVWFLG-CTIFIFGSMVEFAFVNTIW-------RRKKSVPVKKL 360
            ..||:.:...:||||||....: ||:. |..|:|.:::|||.||...       ::|.|.|..::
  Rat   299 MTTLSISARHSLPKVSYATAMD-WFIAVCFAFVFSALIEFAAVNYFTNIQMQKAKKKISKPPPEV 362

  Fly   361 NSKHILKSTLSPNLLRRRSHA--RSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQV 423
            .:..:||...:...| :.:||  ..|..:...:|..:|..|....|.::..|.
  Rat   363 PAAPVLKEKHTETSL-QNTHANLNMRKRTNALVHSESDVNSRTEVGNHSSKTT------------ 414

  Fly   424 LDQQRTSRVVQKMDVNFVESAFGSMG-----SAQSTGAISAASSSQ--TL--------------- 466
             ..|.:|....|..:....:.|....     ||.:.|..||||.|.  ||
  Rat   415 -AAQESSETTPKAHLASSPNPFSRANAAETISAAARGLSSAASPSPHGTLQPAPLRSASARPAFG 478

  Fly   467 -------TNNNRTESAGHQEEIDLSGWTTLTPQEIA--------MWIDSRARFVFPLSFLVFNLF 516
                   |..|.|...|:         .:.||...|        ..||..||.:||::|..||:.
  Rat   479 ARLGRIKTTVNTTGVPGN---------VSATPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMV 534

  Fly   517 FWTFVY 522
            :|. ||
  Rat   535 YWV-VY 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	139/587 (24%)
Gabra4	NP_542154.3	LIC	13..539	CDD:455710	139/589 (24%)
		LGIC_ECD_GABAAR_A4	57..255	CDD:349838	49/237 (21%)
		Cys-loop	172..186	CDD:349838	5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	353..436		17/96 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	448..470		8/21 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	486..513		7/35 (20%)