Protein Alignment CG6927 and Gabrg1

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_542153.1
• Gene: Gabrg1 / 140674
• RGDID: 621732
• Length: 465
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 134/545 - (24%)
• Similarity: 226/545 - (41%)
• Gaps: 120/545 - (22%)

  Fly     3 WS---------LIISILL-NCLYASASALDED---------CPTLDDGDSLSQTQLLDRLTHGCR 48
            ||         |::::.| ||:..:....|||         .|.:.:||.   ||:|:.|..|
  Rat    15 WSQTRGVRLIFLLLTLHLGNCIDKADDEDDEDLTMNKTWVLAPKIHEGDI---TQILNSLLQG-- 74

  Fly    49 YDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNFRNVSPKRR 113
            ||...||    :.|.| |..:....|:..:..::..::::.|..:....:.|.||.|.:.    .
  Rat    75 YDNKLRP----DIGVR-PTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNST----M 130

  Fly   114 QPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKF 178
            :.::...::...:|:|..|..|.|.|....:|..:.|..|..||.|:.:.|:.....|:|.|..|
  Rat   131 KVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNF 195

  Fly   179 PFDEQHCSTVLESWMYNTSELVLHWEQKRPITYD---GALHLTEFVLQRSWSNETVINADLSDLR 240
            |.||..|.....|:.|..:|:...|::......|   ..|:...||..|   |.|.|:..:|
  Rat   196 PMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLR---NSTEISHTIS--- 254

  Fly   241 HGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFI 305
                 |:|..::....|:|.:|::.:..::|.:|.|.:||||||:..|..|.|.:||.:|:||..
  Rat   255 -----GDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMT 314

  Fly   306 TLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVN--TIWRRKKSVPVKKLNSKHILKS 368
            ||::...|:||||||:...:::...|.||:|.:::|:..::  |...:.|:...:||.|    |:
  Rat   315 TLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNNKGKTTRDRKLKS----KT 375

  Fly   369 TLSPNLLRRRSHARSRSFSGTALHKTADTGSLGGAGFNNYLTVNLPITTIKEGQVLDQQRTSRVV 433
            ::||.|     ||      |:.|                     :|:..|...|..|
  Rat   376 SVSPGL-----HA------GSTL---------------------IPMNNISMPQGED-------- 400

  Fly   434 QKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNRTESAGHQEEIDLSGWTTLTPQEIAMWI 498
               |..:                       |.|...:........|:.....|...........|
  Rat   401 ---DYGY-----------------------QCLEGKDCATFFCCFEDCRTGSWREGRIHIRIAKI 439

  Fly   499 DSRARFVFPLSFLVFNLFFWT-FVY 522
            ||.:|..||.:|.:|||.:|. ::|
  Rat   440 DSYSRIFFPTAFALFNLVYWVGYLY 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	133/541 (25%)
Gabrg1	NP_542153.1	LIC	66..462	CDD:455710	120/487 (25%)
		LGIC_ECD_GABAAR_G	88..269	CDD:349801	43/195 (22%)
		Cys-loop	188..202	CDD:349801	7/13 (54%)