Protein Alignment CG6927 and Rdl

DIOPT Version :10

• Sequence 1: NP_572194.1
• Gene: CG6927 / 31419
• FlyBaseID: FBgn0029733
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_316070.4
• Gene: Rdl / 1276697
• VectorBaseID: AGAMI1_011163
• Length: 555
• Species: Anopheles gambiae
• Alignment Length: 529
• Identity: 141/529 - (26%)
• Similarity: 216/529 - (40%)
• Gaps: 85/529 - (16%)

  Fly    31 GDSLSQTQLLDRLTHGCRYDRLERPITYSETGQRLPVDVYMRAYIYFMQNLEAHDLQFKIYALLQ 95
            || ::.:.:||..:.|  ||:..|| .|...    ||:|.:..|:..:.::....:.|.:....:
Mosquito    50 GD-VNISAILDSFSVG--YDKRVRP-NYGGP----PVEVGVTMYVLSISSVSEVLMDFTLDFYFR 106

  Fly    96 MRYLDPRLNFRNVSPKRRQPILGEEHLRNSLWMPHIFLANERDSSILGLTEKDILTSISPDGTVI 160
            ..:.||||.:|. .|......:|.|.::| :|:|..|..||:.|.....|..:....|...|::.
Mosquito   107 QFWTDPRLAYRK-RPGVETLSVGSEFIKN-IWVPDTFFVNEKQSYFHIATTSNEFIRIHHSGSIT 169

  Fly   161 VSNRIKATLYCWLNLKKFPFDEQHCSTVLESWMYNTSELVLHWEQ-KRPITYDGALHLTEFVLQR 224
            .|.|:..|..|.:||:.||.|.|.|...:||:.|...::...|:. ...:.....:.|.:|.:..
Mosquito   170 RSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWKDGLSSVGMSSEVELPQFRVLG 234

  Fly   225 SWSNETVINADLSDLRHGAFAGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQ 289
            .....|.||..         .||||.|:..:...|.:|:||:..::||.|||.||||||||..:.
Mosquito   235 HRQRATEINLT---------TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNA 290

  Fly   290 APPRITLGTSTLLTFITLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTIWRR--- 351
            .|.|:.||.:|:||..||.|:....|||:||:|..:|:...|.:.:|.|::|:|.|..:.:|
Mosquito   291 TPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQM 355

  Fly   352 --------KKSVPVKKLNSKHILKSTLSPNLLRRRSHARSRSFSGTALH-KTADTGSLGGAGFNN 407
                    :|....||............|.:....||......|.|..| .....||..|.
Mosquito   356 RKQRFMAIQKIAEQKKQQQADANHPPPPPPVASDHSHGHGHGHSHTHQHTPKQQMGSRSGT---- 416

  Fly   408 YLTVNLPITTIKEGQVLDQQRTSRVVQKMDVNFVESAFGSMGSAQSTGAISAASSSQTLTNNNR- 471
              ..|:|           ....||....:...|.|..|    ......|.|...:.:...|..|
Mosquito   417 --MQNVP-----------PNMGSRGCSIVGPLFQEVRF----KVHDPKAHSKGGTLENTINGGRG 464

  Fly   472 -----------------------TESAGHQEEI----DLSGWTTLTPQEIAMWIDSRARFVFPLS 509
                                   .|||..|..|    |::....:||.:    ||..:|.|||:.
Mosquito   465 GGQPGGGGPPPGGPPGGGGGGPDEESAAPQHLIHPGKDINKLLGITPSD----IDKYSRIVFPVC 525

  Fly   510 FLVFNLFFW 518
            |:.|||.:|
Mosquito   526 FVCFNLMYW 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6927	NP_572194.1	LIC	3..520	CDD:455710	141/529 (27%)
Rdl	XP_316070.4	LIC	56..537	CDD:455710	139/522 (27%)
		LGIC_ECD_GABAR_RDL-like	78..261	CDD:349809	47/193 (24%)
		Cys-loop	180..194	CDD:349809	7/13 (54%)