DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and slc17a7a

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001092225.1	Gene:	slc17a7a / 795293	ZFINID:	ZDB-GENE-050105-5	Length:	582	Species:	Danio rerio

Alignment Length:	455	Identity:	161/455 - (35%)
Similarity:	244/455 - (53%)	Gaps:	25/455 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IPRCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMVN-HTAISHTKSSTQSKERDGDFEWSYKL 97
            :||    |:.:.::...|...::.:|.|:.||||:||| ||..|..|....:.:    |.|..:.
Zfish    59 LPR----RYIIAILSGLGFCISFGIRCNLGVAIVSMVNDHTVYSGKKPVIVAAQ----FTWDPET 115

  Fly    98 QGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISAR--SGGVVGLCVVRF 160
            .|.|..|||:||::||||.|.:.:.:.|....|:.::..|.....||.:||  .|.|:   :||.
Zfish   116 VGMIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVI---MVRV 177

  Fly   161 IQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFY 225
            .|||.||...|..|.:.|:|.||.|||......:.|:..|.:|:|||:|:|..|   .||.|:||
Zfish   178 CQGLVEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQY---TGWSSVFY 239

  Fly   226 IFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQA----QPEERSRIPFLGIAKSPPF 286
            ::|.....|.:.:|.:..||||....|:..||::|.:||.::    .|.::.:.|:.....|.|.
Zfish   240 VYGSVGIFWYLFWILVSYESPAAHPTITPEERKYIEDAIGESAGLVNPLQKFKTPWRHFFTSMPV 304

  Fly   287 YAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCLIRRN 351
            |||:||:...::.:..|:...|.|...|....|...|::|:||:|.|.|:..:.|.|||.|...|
Zfish   305 YAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMVSALPHLVMTIIVPIGGQLADYLRTHN 369

  Fly   352 FSITV-VRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHLDLSPRF 415
            ...|. ||||||..|....|..|:.||| .|:..:.....:|.:|.:|....||.:||||::||:
Zfish   370 LMTTTNVRKLMNCGGFGMEATLLLVVGF-SHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRY 433

  Fly   416 AGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVFASG-KQQW 479
            |.:|:.::|.|..|.|::.|::.|.:...| :.|.|:.||.|||.|......||.:|||| ||.|
Zfish   434 ASILMGISNGVGTLSGMVCPLIVGAMTKHK-TREEWQYVFLIAALVHYGGVIFYGLFASGEKQPW 497

Fly 480 479
Zfish 498 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	157/448 (35%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	151/435 (35%)
slc17a7a	NP_001092225.1	2A0114euk	62..501	CDD:129972	159/448 (35%)
slc17a7a	NP_001092225.1	MFS	67..490	CDD:119392	151/434 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582517
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.650