DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and slc17a7

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001072608.1	Gene:	slc17a7 / 780064	XenbaseID:	XB-GENE-5742677	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	452	Identity:	156/452 - (34%)
Similarity:	245/452 - (54%)	Gaps:	19/452 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IPRCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQSKERDGDFEWSYKLQ 98
            :||    |:.:.:|...|...::.:|.|:.||||:|||:..:   ....:.......|.|..:..
Frog    59 LPR----RYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNNTV---YKGNKIVIEQAQFTWDPETV 116

  Fly    99 GYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQG 163
            |.|..|||:||::||||.|.:.:.:.|....|:.::..|.....||.:||......:| ||.:||
Frog   117 GMIHGSFFWGYIVTQIPGGYICQKFAANRVFGFAIVATSTLNMLIPSAARVHFACVIC-VRILQG 180

  Fly   164 LGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFG 228
            |.||...|..|.:.::|.||.|||......:.|:..|.:|:|||:|:|..|   .||.|:||::|
Frog   181 LVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQY---SGWSSVFYVYG 242

  Fly   229 LFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQA----QPEERSRIPFLGIAKSPPFYAI 289
            .|..:|.:.:|.:..||||:...|||.|:::|.|:|.::    .|..:.:.|:.....|.|.|||
Frog   243 SFGIMWYMFWILVSYESPAIHPTISEEEKKYIEESIGESTGLMNPMAKFKAPWRKFFTSMPVYAI 307

  Fly   290 LVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCL-IRRNFS 353
            :||:...::.:..|:...|.|...|....|...|::|:||:|.|.|:..:.|.:||.| .:|..|
Frog   308 IVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLLSALPHLVMTIIVPIGGQIADFLRTKRIMS 372

  Fly   354 ITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHLDLSPRFAGL 418
            .|.|||:||..|....|..|:.||: .||..:.....:|.:|.:|....||.:||||::||:|.:
Frog   373 TTNVRKMMNCGGFGMEATLLLVVGY-SHSRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASI 436

  Fly   419 LISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVFASG-KQQW 479
            |:.::|.|..|.|::.|::.|.:...| :.|.|:.||.||:.|......||.:|||| ||.|
Frog   437 LMGISNGVGTLSGMVCPLIVGAMTKHK-TREEWQYVFLIASLVHYGGVLFYGIFASGEKQPW 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	152/445 (34%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	146/432 (34%)
slc17a7	NP_001072608.1	2A0114euk	62..503	CDD:129972	154/445 (35%)
		MFS	67..490	CDD:119392	146/431 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..547
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920