DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001258143.1	Gene:	Slc17a4 / 679784	RGDID:	1584758	Length:	495	Species:	Rattus norvegicus

Alignment Length:	483	Identity:	154/483 - (31%)
Similarity:	242/483 - (50%)	Gaps:	37/483 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ASDGQIPR---------------CRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAI-SH 77
            |.:|.||.               |...|..:..:|.....:.|..:.|:|:||.||||.||. ||
  Rat     9 AREGGIPNDSNLNMTQEQSFKKGCCSLRHGLAFILHLCNFSVYTQQMNLSIAITAMVNTTAASSH 73

  Fly    78 TKSSTQSKERDGD--------------FEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGARHF 128
            ..:|.:....|..              ::|:.::||.:|||..||..:..||.|.:...:||::.
  Rat    74 ANASIERPTTDSQDFWNETLQESKAPVYDWTPEIQGILLSSLNYGSFLAPIPTGYVAGVFGAKYV 138

  Fly   129 LGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAV 193
            :|.|::::|:...|||::|.: ||..|.|:|.|||:.:..::...:|:.|:|.||.|||......
  Rat   139 VGLGLLVSSVLTLFIPLAAEA-GVALLIVLRVIQGMSQVMVLTGQYSMWAKWAPPLERSQLITIA 202

  Fly   194 YAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISEAERR 258
            .:|:..||.:.:...|||..   ..|||.||||||......|:::..||.:.|.....||..|:|
  Rat   203 ASGSMLGTFLVLIAGGLLCQ---ALGWPYIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGEKR 264

  Fly   259 HIMEAIWQAQPEERSRIPFLGIAKSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNG 323
            :||.::.|........:|...:.||.|.:||:|::....:...|:|...|||:..||..|:|.:|
  Rat   265 YIMCSLAQEDCSLGWSLPIKAMVKSLPLWAIVVSYFCEYWLLFTIMAYTPTYISSVLQANLRDSG 329

  Fly   324 IISSLPYLAMWILAIVFGILADCLIRRN-FSITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTS 387
            |:|:||::...:..|:.|:|||.|:.|| ..:..:|||..:||....:..|:.:.:|..||..|.
  Rat   330 ILSALPFMFGCVCIILGGLLADFLLSRNILRLVTIRKLFTALGVLVSSGILVPLPWVSSSLSTTM 394

  Fly   388 VIFILGMGLNGAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWR 452
            ...:|..........|..||.||::||:||.|..:....:.|.|.:||.|||..|. :.|...||
  Rat   395 AFLVLSSVFASLCDSGALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFIS-QDSEFGWR 458

  Fly   453 IVFYIAAGVFIFTASFYNVFASGK-QQW 479
            .||.:||.:.:....||.:|...: |.|
  Rat   459 NVFLLAAAIDVVGLLFYLIFGRAEVQDW 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	147/456 (32%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	145/443 (33%)
Slc17a4	NP_001258143.1	MFS_SLC17	40..479	CDD:340876	145/443 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840