DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6978 and MFS9

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	488	Identity:	163/488 - (33%)
Similarity:	262/488 - (53%)	Gaps:	29/488 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTDTAGVYDSKGVSNRNRSDQEVRME-----RYASDGQIPRCRKTRFFVVLMLFSGMANAYVMRT 60
            |||.....:.|.:...::::.|:...     |:        .||.|:.|||:.|.|..|.|.:|.
  Fly     1 MTDLESPKNGKHLEQVHQNNNEITESEPLTWRF--------WRKQRYIVVLLAFFGFFNVYSLRV 57

  Fly    61 NMSVAIVAMVNHTAISHTKSSTQSKERDGDFEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGA 125
            |:|||||||..:..:.....:...::   ||.|..|.:|.|||||||||::||...|.:....|.
  Fly    58 NLSVAIVAMTENRTVFDADGNVSYQQ---DFPWDSKQKGLILSSFFYGYILTQFLGGYIGTKIGG 119

  Fly   126 RHFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAG 190
            ....|.|:...::.....|::| |..:.....||.|:|..||...|..|::.|:|.||.|||...
  Fly   120 NIVFGTGIGSTAILTLLTPMAA-SHSLEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMA 183

  Fly   191 AAVYAGAQFGTIVSMPLSGLLA-HYGFDGGWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISE 254
            :..:||...||:|:||.||.|| .|    ||.|:||:||....||.|.::..|:..|.:....|:
  Fly   184 SIAFAGNYAGTVVAMPCSGFLATKY----GWESVFYVFGTIGVIWYITWLVFVKAGPELDRFCSK 244

  Fly   255 AERRHIMEAIWQAQPEERSRIPFLGIAKSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNI 319
            .|..:|.:.|... ..:..:.|:..|..|.|||||:.:|...|:|:.||:|.||:::...||.::
  Fly   245 EECDYIQKTIGYV-GSKHVKHPWRAIFTSMPFYAIMASHFSENWGFYTLLTQLPSFLRDTLNFDL 308

  Fly   320 RTNGIISSLPYLAMWILAIVFGILADCL-IRRNFSITVVRKLMNSLGQYGPAVALISVGFVHHSL 383
            ...||:|::|||||.||..|.|.|||.| ::..::.|.||:..|........|.::...::....
  Fly   309 GKTGILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQVRRNFNCGAFLAQTVFMMLTAYLLDPT 373

  Fly   384 WLTSVIFI-LGMGLNGAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPS 447
            |  ||:.: :.:||....:.||.:||||::|:.|.:|:.:.|..|.:.|:::|::.|:|:..:.|
  Fly   374 W--SVVSLTIAVGLGAFAWSGFAVNHLDIAPQHASVLMGIGNTFATIPGIVSPLLTGYVVTNQTS 436

  Fly   448 VENWRIVFYIAAGVFIFTASFYNVFASGK-QQW 479
             :.|||:|:|:||:::.....|..:.||. |:|
  Fly   437 -DEWRIIFFISAGIYLVGCVIYWFYCSGDLQEW 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	155/443 (35%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	149/430 (35%)
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	155/443 (35%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	149/429 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.870