DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and slc37a2

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_998179.2	Gene:	slc37a2 / 406287	ZFINID:	ZDB-GENE-040426-1949	Length:	494	Species:	Danio rerio

Alignment Length:	502	Identity:	109/502 - (21%)
Similarity:	182/502 - (36%)	Gaps:	139/502 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQSKERDGD--FEW------SYK- 96
            ||.::.:.|....:.::.|  ..::||....|...|:..........|.|  .:|      :|:
Zfish    21 RFSILFLTFVFYTSYHLSR--KPISIVKSQLHRNCSNVVHPANLNITDNDTWCDWVPFDGKNYQN 83

  Fly    97 LQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSL--AAFFIPISARSGGVVGLCVVR 159
            |.|.:.:.|...|.:.....|:..:....|::|..||:::.|  |.|.:....:...:...|:|:
Zfish    84 LFGVLDNCFLVAYAVGMFFSGIFGERLPLRYYLSTGMLLSGLFTALFGLGFYWQIHSLWYYCLVQ 148

  Fly   160 FIQGL----GEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGW 220
            .:.||    |...:|.|    :..|....:|........:....|.|    |..|:|.......|
Zfish   149 ALNGLVQTTGWPAVVAC----VGNWFGKGKRGFIMGVWNSHTSVGNI----LGSLIAGVYVSSAW 205

  Fly   221 PSIFYIFGLF--ST-IWCIIFI--------CL-------VQESPAV--STRISEAERRHIMEAIW 265
            ...|.:.|:.  || :.|.:|:        |.       |:|.|.:  |:...|....|...|:
Zfish   206 GLSFIVPGIIIASTGVICFLFLVERPEDVNCTAPQHHERVEEEPLLRNSSTNEEIFNSHTSTAV- 269

  Fly   266 QAQP-EERSR-IPFLGIAKSPP--------FYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIR 320
              :| |:.|. |.|.|..:.|.        .:|.||::        |.:..||.|:..|.:.:.:
Zfish   270 --EPVEDHSEAISFCGALRIPGVVEFSFCLLFAKLVSY--------TFLYWLPLYIANVAHFDPK 324

  Fly   321 TNGIISSLPYLAMWILAIVFGILAD--------CLIRRNFSITVVRK----LMNSLGQYG-PAVA 372
            ..|.:|:|..:...:..||.|:::|        |.     ::.::..    |.|.:||.| |.
Zfish   325 KAGDLSTLFDVGGILGGIVAGLVSDYTGGRASTCC-----AMLIIAAPMLFLYNKIGQNGLPT-- 382

  Fly   373 LISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKIN----------------HLDLSPRFAGL--- 418
              :||.:   ||                 ||..:|                |..|......|
Zfish   383 --TVGML---LW-----------------CGALVNGPYALITTAVSADLGTHESLRGNSRALSTV 425

  Fly   419 --LISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFY--IAAGV 461
              :|..|..:...||   |::|| :|.|    ..|..|||  |||.|
Zfish   426 TAIIDGTGSIGAAVG---PLLAG-LISP----TGWNNVFYMLIAADV 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	109/502 (22%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	107/498 (21%)
slc37a2	NP_998179.2	UhpC	20..470	CDD:332119	109/502 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582660
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930