DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6978 and CG3649

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	143/457 - (31%)
Similarity:	225/457 - (49%)	Gaps:	42/457 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQSKERDGDFEWSYKLQGYILSSF 105
            |...||.||.........|.||||||||..|         :..|.....::..:...:.|.:||.
  Fly    18 RHLQVLFLFLCATLIVAQRFNMSVAIVAFTN---------ANSSNPNYPEYRLTEPQKSYTISSP 73

  Fly   106 FYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQGLGEGPIV 170
            |:|...||:..|.:...:||:..|...|::.:|.:...|.:...||...|..|||:|||..|.:.
  Fly    74 FWGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMW 138

  Fly   171 PCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFGLFSTIWC 235
            ||.::.||:|.|..|.:..|..:..|...|||:...|||:|:....  ||||.||:.|....:||
  Fly   139 PCLYTHLAKWCPKKEANRMGGIMTTGLDCGTIMGFALSGVLSASPL--GWPSTFYVPGYLGIVWC 201

  Fly   236 IIFICLVQESPAVSTRISEAERRHIMEAIWQAQPEERSR--IPFLGIAKSPPFYAILVAHAGHNY 298
            :.|:.....||:.|..||.|||:||..|:.|.|....:.  :|:|.|..|.||..:.........
  Fly   202 LTFLRYGANSPSESKFISLAERKHIQFALEQNQVIRGATPPVPWLQILTSRPFIVLAFCKMSQAC 266

  Fly   299 GYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCLI-RRNFSITVVRKLMN 362
            .:.|||..:|.|::.:.:.:|..|.::|:||::.|.:.:..|..||:.|. ||:.|:.::||.:|
  Fly   267 SFYTLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIFLAEYLTRRRDISLPILRKTIN 331

  Fly   363 SLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLNGAIYC-------------GFKINHLDLSPR 414
            |...:.|||||:.:.:|...    :|:        |:::|             |..:||:||||.
  Fly   332 SFATWTPAVALVILSYVSDQ----NVV--------GSMFCLIAATAAISGQAIGSSLNHVDLSPN 384

  Fly   415 FAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTAS-FYNVFAS-GKQ 477
            |||||..::|.:.:..|:::|:|.|..:..:.....||.|| :...|.:|..: .|.:|.. ..|
  Fly   385 FAGLLFGMSNTLMSAAGVISPIVIGLTVTKESDRSQWRTVF-LGISVILFLGNLMYLIFGQMTVQ 448

  Fly   478 QW 479
            .|
  Fly   449 SW 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	141/454 (31%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	139/444 (31%)
CG3649	NP_611725.2	MFS	22..442	CDD:119392	139/443 (31%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	141/452 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451976
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D46132at33392
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900