DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6978 and CG9254

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster

Alignment Length:	451	Identity:	159/451 - (35%)
Similarity:	257/451 - (56%)	Gaps:	20/451 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RFFVVLMLFSGMANAYVMRTNMSVAIVAMV---NHTAISHT--------KSSTQSKERDGDFEWS 94
            |:.:.:|.|..:.|||.||..:|.||..:|   |:| |.||        :|...|....||::||
  Fly    23 RWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYT-IFHTEAICEPDDQSDPSSTFEGGDYDWS 86

  Fly    95 YKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVR 159
            .:.||.||:||:.||::|.:|.|::...:|.:..|..|:...::.....|:....||...|.|:|
  Fly    87 QEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCIVYGGADALIVLR 151

  Fly   160 FIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIF 224
            .:.|||||...|....|||.|||.|||.:.||.|..|.|.|:|....:||.:.. ..|  ||.:|
  Fly   152 VLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLS-SMD--WPWVF 213

  Fly   225 YIFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQPEE-RSRIPFLGIAKSPPFYA 288
            |:|.:.:.:|.::|..:...||.....|...||..:.:.:  ..|:: :.:.||..|..|.|.:|
  Fly   214 YVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEV--PPPDKNKPKTPFFAILTSIPMWA 276

  Fly   289 ILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCLIRRN-F 352
            ::.|..||::|:..:::.||.||..||..:|::||:.|||||:.|||::::.|.:||.:|:|| .
  Fly   277 LISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVADQMIKRNCM 341

  Fly   353 SITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHLDLSPRFAG 417
            |.|..||:|..:..:||||.:::..:...:..:...:|.:.|||.|..|.|.|:..||:||.:||
  Fly   342 STTNTRKIMTGVAAFGPAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLDMSPNYAG 406

  Fly   418 LLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVFASGKQQ 478
            .|:::||.:..:.|:::|.:.| |:.|..::..||:||::|.||.:.||..|.::|||..|
  Fly   407 TLMAITNGIGAITGVVSPYLVG-VMTPNATLLEWRLVFWVAFGVLVVTAIVYCIWASGDVQ 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	158/449 (35%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	154/440 (35%)
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	157/444 (35%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	135/384 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452006
Domainoid	1	1.000	270	1.000	Domainoid score	I959
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.890