DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6978 and Slc37a1

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001011944.1	Gene:	Slc37a1 / 294321	RGDID:	1308587	Length:	537	Species:	Rattus norvegicus

Alignment Length:	518	Identity:	106/518 - (20%)
Similarity:	186/518 - (35%)	Gaps:	138/518 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAI------------SHTKSS------TQSKER 87
            |.|:.::.|...|:.::.|..:|:....:....|.            |.|:.|      ....|.
  Rat    21 RAFIFMLTFLLYASFHLSRKPISIVKGELHKQCAAADEPEPRFGGPSSSTRRSPTHWLLNNETET 85

  Fly    88 DGDFEWS-------YKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSL------A 139
            :.|..|:       .:|.|.:..:|...|.|.....|::.:....|::|.:||:.:..      .
  Rat    86 ETDCGWAPFDKNNYQQLLGALDYAFLCAYAIGMYLSGIIGERLPIRYYLTFGMLASGAFTALFGL 150

  Fly   140 AFFIPISARSGGVVGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVS 204
            .:|..|.:....||...:...:|..|...:|.|    |:.|.....|.|......:....|.|
  Rat   151 GYFYNIHSLGFYVVTQIINGLVQTTGWPSVVTC----LSNWFGKGRRGLIMGIWNSHTSVGNI-- 209

  Fly   205 MPLSGLLAHYGFDGGWPSIFYIFG-LFSTIWCIIFICLVQE------SPAVST--RISE------ 254
              |..|:|.|.....|...|.:.| :...:..:.|:.|::.      |..:.|  |.||
  Rat   210 --LGSLIAGYWVSTCWGLSFIVPGAIVGAMGIVCFLFLIEHPKDIKCSSTLPTHPRASENGINRF 272

  Fly   255 --------AERR----------------------HIMEAIWQAQPEER----SRIPFLGIAKSPP 285
                    :|:.                      ||:     ..|.:|    :.|.|.|..:.|.
  Rat   273 RVQKQTTHSEKNGPLDPELQCLLLSDGKSPLHPSHIV-----VLPGDRTSSMAAISFTGALRIPG 332

  Fly   286 --------FYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGI 342
                    .:|.||::        |.:..||.|:..|.:::.:..|.:|:|..:......|:.|:
  Rat   333 VIEFSLCLLFAKLVSY--------TFLFWLPLYITNVDHLDAKKAGELSTLFDVGGIFGGILAGV 389

  Fly   343 LADCLIRRNFSITVVRKL-------MNSLGQYG----PAVALISVGFVH--HSLWLTSVIFILGM 394
            ::|.|.:|..:..::..|       .:|:.:.|    .|:.|:|...|.  ::|..|:|...||
  Rat   390 ISDRLEKRASTCGLMLLLAAPTLYVFSSVSKMGLEATIAMLLLSGALVSGPYALITTAVSADLG- 453

  Fly   395 GLNGAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYI 457
                 .:...|.|...||...|  :|..|..|...:|   |::|| :|.|    ..|..|||:
  Rat   454 -----THKSLKGNSHALSTVTA--IIDGTGSVGAALG---PLLAG-LISP----SGWSNVFYM 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	106/518 (20%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	104/514 (20%)
Slc37a1	NP_001011944.1	MFS_SLC37A1_2	21..520	CDD:340902	106/518 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342625
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930