DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and SPAC1002.16c

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_593504.1	Gene:	SPAC1002.16c / 2543262	PomBaseID:	SPAC1002.16c	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	466	Identity:	102/466 - (21%)
Similarity:	181/466 - (38%)	Gaps:	101/466 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 TNMSVAIVAMVNHTAISHTKSSTQSKERDGDFEWSYKLQG----YILSSFFYGYVITQIPFGLMI 120
            |.|.:.:||.::.:.|.:.|.:...::        .||:|    .|.|.|:..:::.::|..|::
pombe    62 TIMILYLVAFLDRSNIGNAKVAGLPED--------LKLKGDQFNIIASVFYVTFILFEMPTTLLM 118

  Fly   121 KYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQGLGEGPIVPCSHSLLAQW----- 180
            |....:..|.:.::..||...|.......|   ||...|.:.|..|..:.||    ||.:
pombe   119 KKVQPKRMLAFIVISYSLTTIFTGFCHNFG---GLLAARLVLGFCEAGLFPC----LALYLTMIY 176

  Fly   181 ----VPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFGLFSTIWCIIFICL 241
                :.|....|..::..:|| ||.:.:..:..:....|| .||..:|.|.||      |.|:|.
pombe   177 SRVELAPRIAYLFASSALSGA-FGGLFAYAVLHMDGVGGF-AGWRWLFIIEGL------IGFVCG 233

  Fly   242 VQESPAVSTRISEA---ERRHIMEAIWQAQPE-----ERSRIPFLGIAKSP----PFYAILVAHA 294
            |.....:...|::|   .:.| .|.:.:.|.|     |.:...:.|: ||.    ..|...::..
pombe   234 VAVYFIIPNDITKAWFLSKTH-QEMMRKRQLERAADLEAAHFDWKGV-KSAFTDFKVYLYALSEF 296

  Fly   295 GHN---YGYETLMTMLPTYM-YRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCLIRRNFSIT 355
            |.:   ||:.|.:..:.:.| |..|:|...|         :.::||.....|.|..|..|...
pombe   297 GQDTCLYGFSTFLPAIISGMGYTSLSVQYMT---------IPVYILGAATYIAASFLSDRFHH-- 350

  Fly   356 VVRKLMNSLGQYGPAVALI-------SVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHL--DL 411
              |.::..:|...|.|..|       :...::.:.:|.||....|.|||        :..|  ::
pombe   351 --RGIILIIGNIFPIVGYILLLACQNNKSVLYFACYLCSVGVYTGAGLN--------VTWLSANI 405

  Fly   412 SPRF-AGLLISVTNCVANLVGLMA--------PMVAGHVIDPKPSVENWRIVFYIAAGVFIFTAS 467
            :|.: ....||:...:||..|::|        ..:|||:..        .|..:|:..:.:....
pombe   406 APHYKRATAISLQLAIANSSGILAGQIYRYPPKYIAGHLTS--------LIAIFISTVLHVVNIF 462

  Fly   468 FYNVFASGKQQ 478
            |.....|.||:
pombe   463 FLKHQNSKKQK 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	101/464 (22%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	99/459 (22%)
SPAC1002.16c	NP_593504.1	MFS	63..455	CDD:119392	97/445 (22%)
SPAC1002.16c	NP_593504.1	2A0114	65..435	CDD:273326	91/415 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050