DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and SPCC757.13

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_587688.1	Gene:	SPCC757.13 / 2539039	PomBaseID:	SPCC757.13	Length:	522	Species:	Schizosaccharomyces pombe

Alignment Length:	526	Identity:	106/526 - (20%)
Similarity:	193/526 - (36%)	Gaps:	172/526 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DSKGVSNRNRSDQEVRMERYASDG---QIPRCRKTRFFVVLMLFSGMANAYVM----RTNMS-VA 65
            |::|.::      .|..|..|.|.   .....|:..:.:.|::...|...|::    :|.:| .|
pombe    41 DAEGTAD------AVAQELLADDDFTYTAKEARRVLWKIDLVMMPVMCITYMIQYLDKTALSYAA 99

  Fly    66 IVAMVNHTAI-SHTKSSTQSKERDGDFEWSYKLQGYILSSFFY-GYVITQIPFGLMIKYYGARHF 128
            :..|...|.| .||.||                    :::.|| ||::.|.|..::::.....:|
pombe   100 LYGMKTDTHIDGHTYSS--------------------MTTLFYAGYLVAQYPAAILMQKCRLSYF 144

  Fly   129 LG-----WGMMINSLAAFFIPISARSG-GVVGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERS 187
            :.     |..|:..:||      .|:| .::||   ||:.|:.|..|.|...::.|.|....|:.
pombe   145 IFCNVFLWSAMVCLMAA------CRNGPSLLGL---RFLAGIFEASITPAFINITAMWYRREEQP 200

  Fly   188 LAGAAVYAGAQFGTIVSMPLSGLLAH-YGFDGGWPSIFYIFGLFSTIWCIIFICLVQESPAVSTR 251
            :.....||......|:...||..|.| :|....|..:|.:.||.|..|.::|: .:..:|:.:..
pombe   201 MRTLCWYAFNGIAQIIGSILSYGLGHIHGKVASWRYVFIVIGLMSLGWGVVFV-FIPSNPSKARF 264

  Fly   252 ISEAERRHIMEAI-------------WQ------AQPEERSRIPFLGIAKSP----PFYAILVAH 293
            :|..|:|..:|.:             |:      ..|:......|.|:....    .|..:::..
pombe   265 LSSREKRIALERVRDNRTGLENKQFKWKHAYEAFLDPQVIMITLFTGVCMITNGIGVFSTLIIKG 329

  Fly   294 AGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAI----------VFGILADCLI 348
            .|:|..:..::.| |                :.::...||:|..:          :.|:..:||.
pombe   330 LGYNELHSAVLNM-P----------------LGAIEVAAMFISGVLCKVFKNGRLLIGVFMNCLT 377

  Fly   349 RRNFSITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHLDLSP 413
            ..  ...::.|:.:| ..||   .|:.|.|   ::|:                           |
pombe   378 LA--GCLMIWKIPDS-NPYG---RLVGVWF---TMWV---------------------------P 406

  Fly   414 RFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNV------- 471
            ..:.||:|          |::..|||:.   |.:|        .:|.||:    ||:|
pombe   407 ASSALLLS----------LISSNVAGYT---KKTV--------TSATVFV----FYSVGNIVSPQ 446

  Fly   472 -FASGK 476
             |.||:
pombe   447 LFKSGQ 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	100/494 (20%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	96/482 (20%)
SPCC757.13	NP_587688.1	MFS	80..477	CDD:119392	98/481 (20%)
SPCC757.13	NP_587688.1	2A0114	83..478	CDD:273326	97/478 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
TreeFam	0	0.000	Not matched by this tool.
	4	4.050