DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6978 and Slc17a5

DIOPT Version :10

Sequence 1:NP_572188.1 Gene:CG6978 / 31413 FlyBaseID:FBgn0029727 Length:479 Species:Drosophila melanogaster
Sequence 2:NP_766361.1 Gene:Slc17a5 / 235504 MGIID:1924105 Length:495 Species:Mus musculus


Alignment Length:459 Identity:168/459 - (36%)
Similarity:269/459 - (58%) Gaps:20/459 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 PRCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMV-NHTAISHTKSSTQSKERDG--------- 89
            |.|...|:.:.::.|.|....|.:|.|:|||:|.|| ::|.::..::|.:..|...         
Mouse    33 PVCCSARYNLAILAFCGFFVLYALRVNLSVALVDMVDSNTTLTDNRTSKECAEHSAPIKVHHNHT 97

  Fly    90 --DFEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGV 152
              .::|..:.||:||.||||||::||||.|.:....|.:..||.|::..|:...|.|::| ..||
Mouse    98 GKKYKWDAETQGWILGSFFYGYIVTQIPGGYIASRVGGKLLLGLGILGTSVFTLFTPLAA-DLGV 161

  Fly   153 VGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFD 217
            |.|.|:|.::|||||...|..|::.:.|.||.|||......|||||.||::|:||||::.:|   
Mouse   162 VTLVVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGIICYY--- 223

  Fly   218 GGWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQPEERSRIPFLGIAK 282
            ..|..:||:||:...:|.|:::.:|.::|.....||..|:.:|:.:: :.|...:..:|:..|.|
Mouse   224 MNWTYVFYLFGIVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSSL-KNQLSSQKVVPWGSILK 287

  Fly   283 SPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCL 347
            |.|.:||:|||..:|:.:.||:|:|||||..:|..|::.||.:|:|||...|:..|:.|..||.|
Mouse   288 SLPLWAIVVAHFSYNWSFYTLLTLLPTYMKEILRFNVQENGFLSALPYFGCWLCMILCGQAADYL 352

  Fly   348 -IRRNFSITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHLDL 411
             ::.|||...||::.:.:|..||||.|::.||:.....|......:...|.|....||.|||||:
Mouse   353 RVKWNFSTISVRRIFSLVGMVGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFASSGFSINHLDI 417

  Fly   412 SPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVFASGK 476
            :|.:||:|:.:||..|.:.|:..|::| ..:.|..::..|:.||.|||.:.:|.|.|:.:||.|:
Mouse   418 APSYAGILLGITNTFATIPGMTGPIIA-KSLTPDNTIREWQTVFCIAAAINVFGAIFFTLFAKGE 481

  Fly   477 -QQW 479
             |.|
Mouse   482 VQSW 485

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6978NP_572188.1 MFS_SLC17 46..473 CDD:340876 160/439 (36%)
Slc17a5NP_766361.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..25
Dileucine internalization motif. /evidence=ECO:0000250|UniProtKB:Q9NRA2 22..23
MFS_SLC17A5 42..478 CDD:340939 160/441 (36%)
Blue background indicates that the domain is not in the aligned region.

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