DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and Slc17a9

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_898984.3	Gene:	Slc17a9 / 228993	MGIID:	1919107	Length:	447	Species:	Mus musculus

Alignment Length:	459	Identity:	118/459 - (25%)
Similarity:	200/459 - (43%)	Gaps:	69/459 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PRCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQSKERDGDFEWSYKLQG 99
            |.|:.....::|    |....|..|..|.|..|||                  ..||.|:.|..|
Mouse    32 PECQAWTGILLL----GTCLLYCARVTMPVCTVAM------------------SQDFGWNKKEAG 74

  Fly   100 YILSSFFYGYVITQIPFGLMIKYYGARHFL-----GWGMMINSLAAFFIPISAR--SGGVVGLCV 157
            .:|||||:||.:||:..|.:....|....:     .||.:     ....|:.|.  ||.:..|..
Mouse    75 IVLSSFFWGYCLTQVVGGHLGDRIGGEKVILLSASAWGFI-----TVTTPLLAHLGSGHLAFLTF 134

  Fly   158 VRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPS 222
            .|.:.||.:|...|...|||:|.|..:||:...:.|.||:|.||:|:..:..:|..   ..||.|
Mouse   135 SRILTGLLQGVYFPALTSLLSQKVQESERAFTYSTVGAGSQVGTLVTGGVGSVLLD---QCGWQS 196

  Fly   223 IFYIFGLFSTIWC-IIFICLVQESPAVSTRISEAERRHIMEAIWQAQPEER-SRIPFLGIAKSPP 285
            :||..|..:.:|. .::..|:.|...|..          :..:.|..|..: |::|:..:.:...
Mouse   197 VFYFSGGLTLLWAYYVYRYLLNEKDLVLA----------LGFLAQGLPVTKPSKVPWRQLFRKAS 251

  Fly   286 FYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNG-IISSLPYLAMWILAI---VF-GILAD 345
            .:|.:.:.......:..|::.|||:......   .:.| :.:.:|    |:|||   :| |.::|
Mouse   252 VWAAICSQLCSACSFFILLSWLPTFFKETFP---NSKGWVFNVVP----WMLAIPASLFSGFISD 309

  Fly   346 CLIRRNFSITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFI-LGMGLNGAIYCGFKINHL 409
            .||.:.:.:..|||.|..:|....::..:.:|  |.:.:|.::||. ..:|.....:.|..:|..
Mouse   310 RLISQGYRVITVRKFMQVMGLGLSSIFALCLG--HTTSFLKAMIFASASIGFQTFNHSGISVNIQ 372

  Fly   410 DLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVFAS 474
            ||:|..||.|..|.|....|.|::...::|::|:   :..:|..||::.|.:.......:.||
Mouse   373 DLAPSCAGFLFGVANTAGALAGVVGVCLSGYLIE---TTGSWTCVFHLVAIISNLGLGTFLVF-- 432

  Fly   475 GKQQ 478
            ||.|
Mouse   433 GKAQ 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	115/454 (25%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	112/442 (25%)
Slc17a9	NP_898984.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		MFS	40..432	CDD:119392	111/443 (25%)
		2A0114	43..424	CDD:273326	111/432 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810