DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_006516709.1	Gene:	Slc17a2 / 218103	MGIID:	2443098	Length:	480	Species:	Mus musculus

Alignment Length:	473	Identity:	148/473 - (31%)
Similarity:	242/473 - (51%)	Gaps:	34/473 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PRCRK------TRFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHT-----AISHTKS------ST 82
            |..||      .|:.:.|::..........|.::|:||:||||.|     |.:.|:.      |.
Mouse     5 PTTRKGSGFCSLRYALALIMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASTEGPVMDLLSN 69

  Fly    83 QSK------ERDGDFEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAF 141
            ||:      .|...::||.:.||.|.||..||.::|.||.|.:...:||:..||.|::|:||...
Mouse    70 QSRGIKDFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTL 134

  Fly   142 FIPISARSGGVVGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGT--IVS 204
            |.|::| ..||:.:.|:|.:||:.:|.......::.|:|.||.|||...:...:|...|:  ::.
Mouse   135 FTPLAA-DFGVILVIVIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGEDVGSVWVLH 198

  Fly   205 MPLSGLLAHYGFDGGWPSIFYIFGL-FSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQ 268
            .||.|.:...|..    ..||:..| ...:.|:::..::.:.|.....||..|:.||..::.|..
Mouse   199 HPLCGRINLTGTG----LAFYLLHLCIGCVCCVLWFTVIYDDPMHHPCISVREKEHITSSVAQQS 259

  Fly   269 PEERSRIPFLGIAKSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAM 333
            ...|..:|...:.:..|.:||.:....|.:....::|.||||:..||:||||.:|::||||::|.
Mouse   260 SSPRRSVPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAA 324

  Fly   334 WILAIVFGILADCLIRRN-FSITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLN 397
            ....|:.|.:||.|:.|| .|:..||||.:|||...|::..:::.||..|...|.|:.||..|.:
Mouse   325 SSCTILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSYIATIVLLILIPGTS 389

  Fly   398 GAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVF 462
            .....||.||.||::||:|..|:.::.......|:::....|.:|. :.|...||.||:::|.|.
Mouse   390 NLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLIS-QDSESGWRNVFFLSAAVN 453

  Fly   463 IFTASFYNVFASGK-QQW 479
            :|...||.:|...: |.|
Mouse   454 MFGLIFYLIFGQAEIQSW 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	145/467 (31%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	141/448 (31%)
Slc17a2	XP_006516709.1	MFS_SLC17	21..464	CDD:340876	141/448 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838809
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5551
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.700