DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and T22F3.7

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001309505.1	Gene:	T22F3.7 / 188751	WormBaseID:	WBGene00020697	Length:	453	Species:	Caenorhabditis elegans

Alignment Length:	460	Identity:	112/460 - (24%)
Similarity:	196/460 - (42%)	Gaps:	65/460 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RFFVVLMLFSGMANAYVMRTNMSVAIVAMVN-----HTAISHTKSSTQSKERDGDFEWSYKLQGY 100
            |..|:|:.|..:|:.......::...:.|.:     .|.|:.||.|.        ::::.|.:.:
Worm     8 RLIVLLIGFLCLASLCSNYLIINFTFICMKHDLSDGFTEINGTKYSI--------YDYTSKDKTW 64

  Fly   101 ILSSFFYGYVITQIPFGLMIKYYGAR-HFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQGL 164
            |:.|...|.:|..||..:|...|||| .||..| :::.:|...||:||: .....|..:||:||.
Worm    65 IIWSVAAGTIIGTIPLNMMYVKYGARIPFLIAG-LVSCIATALIPLSAQ-WNFFFLIFLRFVQGF 127

  Fly   165 GEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYI--- 226
            ...........:..:|.|.:|.:|..|.:.......:..:...:||:.....  ||...:|:
Worm   128 CYSADFAAIGLMTVRWAPLSETALFVAVLTCFNGIASTFTNFATGLICESSL--GWKWAYYVHAI 190

  Fly   227 --FGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQPEERSRIPFLGIAKSPPFYAI 289
              |.||. :|.:::|    :.|..:.|:|..|.:.|.:...:|...::..:|::.:..||   .|
Worm   191 VGFVLFG-LWLLVYI----DHPQETKRVSRKELQKIQKNKSEAHLSKKCDVPYMKLVTSP---VI 247

  Fly   290 LVAHAGHNYGYE-----TLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAI------VFGIL 343
            |...|  |..:|     ...|.:|.|::.||...:...|..:||      ||.|      ||.::
Worm   248 LCVWA--NAFFELTAAIMFSTYIPLYLHEVLKFGVTETGFYASL------ILGISLPVRFVFALI 304

  Fly   344 ADCL--IRRNFSITVVRKLMNSLGQYGPAVALISVGFV--HHSLWLTSVIF-ILGMGLNGAIYCG 403
            :|.|  :...|.|.....:  |:|..|...|.|  ||:  .:..|  |:.| |:.|...|....|
Worm   305 SDKLKFVSEIFKIHTFNTI--SVGLSGLFFACI--GFIPMENRGW--SLFFCIMTMCCIGVNSGG 363

  Fly   404 FKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASF 468
            |..:.:..|.:|:.::|:....:..|...:||.:....:..:.:...|..||.|..|:.|.|
Worm   364 FYKSGVLHSRQFSHVVITAIQWMKCLALFVAPALVSIFVHEESNRLQWIWVFLIVGGLMIIT--- 425

  Fly   469 YNVFA 473
             |:.|
Worm   426 -NIVA 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	112/460 (24%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	109/454 (24%)
T22F3.7	NP_001309505.1	MFS	10..428	CDD:391944	110/455 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160315
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740