DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and C18D1.2

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_496174.2	Gene:	C18D1.2 / 182781	WormBaseID:	WBGene00007669	Length:	478	Species:	Caenorhabditis elegans

Alignment Length:	469	Identity:	103/469 - (21%)
Similarity:	205/469 - (43%)	Gaps:	54/469 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 KTRFFVVL--MLFSGMANAYVMRTNMSVAIVAMV-NHTAISHTKSSTQ------SKERDGDFEWS 94
            :||||::.  :|...::.:..:..|.::..::.: |.||...::.||.      .|.....:.::
Worm    13 RTRFFILFLCLLCLSISQSNTLTLNFTIICMSTLHNFTATEASEKSTNVLDFMLHKILQKTYVYT 77

  Fly    95 YKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVR 159
            ......:.|:...|.:....||..:|:..|:|..:.:..:.::.....||.:|.. |...|..:|
Worm    78 ASQSNLLFSAVAIGAMCAVYPFMYIIQKKGSRSVVTFVGLFSAATTAMIPWAAYL-GFYPLLAMR 141

  Fly   160 FIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIF 224
            |:||:|..........:..||....:.:...|.:....|.|.|.:||::.......|  |||:::
Worm   142 FLQGIGLSTGFTLIGIVTRQWSMQVQGAFFFACLSCFFQIGPIFTMPVASAFCTSSF--GWPAVY 204

  Fly   225 YIFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQPE-ERSRIPFLGIAKSPPFYA 288
            |...:.:....::|..|.:|||...|.::|.|    :..|.:.:.| :|.|:|.:.|.:.|...:
Worm   205 YTHSIVTIFIFLLFFTLYRESPVFHTIVTELE----LSKIQRGKGETKRQRVPLVQILRDPVVLS 265

  Fly   289 ILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILAD---CLIRR 350
            |......:..|.:..|...|||::::|..:::..|..|:||.:....:.:..|..||   |...:
Worm   266 IWTTALANFMGIQLTMQFTPTYLHKILGFSVQDTGPFSALPQVITAFVKVSAGYSADKLQCCTPK 330

  Fly   351 NFSITVVRKLMNSLGQYGPAVALISVGFVHHSL-WLTSVIFILGMGLNG----------AIYCGF 404
                |.|| :.|||...|.:...:.:..:..|: :|...:.||...:.|          |||..
Worm   331 ----TSVR-IFNSLALGGMSFMFVGLAIIPTSMPYLGLFMLILSCSIIGFNCGGFFRCSAIYAA- 389

  Fly   405 KINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYI--AAGVFIFTAS 467
            :.||      |...:.|..||:|   .|:||::....::.    :.|...:::  :..|.:|.::
Worm   390 QHNH------FVMGMNSFLNCLA---ALLAPVIVNIFVEN----DTWNEWYWVWMSHFVILFLSN 441

  Fly   468 F-YNVFASGK-QQW 479
            . :.::|.|: .:|
Worm   442 LVFQIYAKGEPAEW 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	102/466 (22%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	96/454 (21%)
C18D1.2	NP_496174.2	MFS	36..448	CDD:391944	95/437 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160303
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740