DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and T22F3.11

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_504015.1	Gene:	T22F3.11 / 178782	WormBaseID:	WBGene00020700	Length:	453	Species:	Caenorhabditis elegans

Alignment Length:	471	Identity:	95/471 - (20%)
Similarity:	180/471 - (38%)	Gaps:	85/471 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 TRFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQSKERDGDFEWSYKLQG----Y 100
            :.|.|:...|      ..|:.:||.|:.                  :.:|.....|...|    :
Worm    26 SNFIVINFTF------ICMKNDMSDAVT------------------DSNGTLRSIYDYNGSEKKW 66

  Fly   101 ILSSFFYGYVITQIPFGLMIKYYGAR--HFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQG 163
            ||.:...|.::..:|..::...||||  .|:.....|.|.|  .||.:|.....: |.::||.||
Worm    67 ILWAVALGTMLGTVPINMLYVKYGARLPFFIAGLTSIISTA--LIPWAAGFNYWI-LILLRFCQG 128

  Fly   164 LGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFG 228
            |...........:..:|.|..|.:...|.:.:.....::.:..::|::....:  ||...:|:..
Worm   129 LAYSADFAAIGLITVRWAPLTETATFIAVMTSFTGISSVATNSVTGVICESSY--GWKYSYYLHA 191

  Fly   229 ----LFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQPEERSRIPFLGIAKSPPFYAI 289
                |...:|.|::|    :.|..:.|:|..|...|.::...|..::.:.:|:..:..||..:.:
Worm   192 IVGLLLFVLWYIVYI----DHPQDTKRVSCKELTKIEKSKSAAHLDKSTDVPYRKLLTSPVIWCV 252

  Fly   290 LVAHAGHNYGYE-----TLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWI-LAIVFGILADCLI 348
            .:     |..:|     ...|.:|.|.:.||...:...|...:| .|.:|: :..|..:|:|
Worm   253 WL-----NAFFEMSAVIVCSTYMPIYFHEVLKFGVTETGFWVAL-VLFIWLPVRWVAAVLSD--- 308

  Fly   349 RRNFSITVVRKL-----MNSLGQYGPAVALISVGFV--HHSLW----LTSVIFILGMGLNGAIYC 402
                .|..:.:|     .|::...|.......:||:  .:..|    .|..:..:|:...|...|
Worm   309 ----KIRCIGELPKILIFNTIAVGGTGAFFAVIGFIPAENKYWSVAAFTMTMCCVGVNSGGFYKC 369

  Fly   403 GFKINHLDLSPRFAGLLISV---TNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIF 464
            |  :.|   :.::|.::|:.   |.|||.   ..||.:....:..:.....|..||.:..|:...
Worm   370 G--VLH---ARQYAHVVIAAIQWTKCVAL---FSAPAMVALFVTTESVRTQWIGVFLVFGGLMQI 426

  Fly   465 TASF-YNVFASGKQQW 479
            |... |.:|.....:|
Worm   427 TNLLSYCIFTDKPAEW 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	94/468 (20%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	91/458 (20%)
T22F3.11	NP_504015.1	MFS	11..435	CDD:391944	93/462 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160336
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.850