DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and T22F3.8

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_504013.1	Gene:	T22F3.8 / 178781	WormBaseID:	WBGene00020698	Length:	482	Species:	Caenorhabditis elegans

Alignment Length:	458	Identity:	103/458 - (22%)
Similarity:	194/458 - (42%)	Gaps:	44/458 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RFFVVLMLFSGMANAYVMRTNMSVAIVAMVN-----HTAISHTKSSTQSKERDGDFEWSYKLQGY 100
            ||.|:|:.|..:|:.......::...:.|.:     .|.|:.|:.|......| |.:|
Worm    40 RFIVLLVGFLCLASLCSNYLIINFTFICMKHDFSDGFTEINGTRQSIYDYTPD-DKKW------- 96

  Fly   101 ILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQGLG 165
            ||.:...|.:|..:|..|::..||||.......:::.::...||.:|: .....|.::|||||..
Worm    97 ILWAVAAGTIIGTVPMNLLLVKYGARFPFFLSGIVSCISTSLIPFAAK-WNFAFLIILRFIQGFS 160

  Fly   166 EGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQ--FGTIVSM---PLSGLLAHYGFDGGWPSIFY 225
            ..........|..:|.|     ||..|::....  |..|.||   ..:||:.....  ||...:|
Worm   161 FSADFAAIGLLAVRWAP-----LAETAIFVAVLTCFNAIASMITNMATGLICVSSL--GWKWSYY 218

  Fly   226 IFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQPEERSRIPFLGIAKSPPFYAIL 290
            :..:...|..:::..:..:.|..:.|:|..|.:.|.:...:|...::..:|::.:|.||   .||
Worm   219 LHSIVGAILFVLWYFVYIDHPQDTRRVSGKELQSIQKNKSEAHLSKKCDVPYIKLATSP---VIL 280

  Fly   291 VAHAGHNYGYETLM---TMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCLIRRNF 352
            ...|...:.....:   |.:|.|::.||...:...|..|||.:.....:.:.|||::|.:  :..
Worm   281 CVWANAFFDLTAAIMFSTYIPLYLHEVLKFGVTETGFYSSLIHGICLPVRLCFGIISDKI--QFI 343

  Fly   353 SITVVRKLMNSLGQYGPAVALISVGFV--HHSLW--LTSVIFILGMGLN-GAIYCGFKINHLDLS 412
            |..|..::.|::...|..:...|:|.:  .:..|  .:.::.:..:|:| |..|   |:..|. |
Worm   344 SEPVKIQIFNTISVGGSGLFFASIGLIPMEYRGWSVFSCIMTMSCIGVNPGGFY---KVAVLH-S 404

  Fly   413 PRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVFASGK- 476
            .:||.::::....:..|...:||.:....:..:...:.|..||.|..|..:.|......|.:.|
Worm   405 RQFAHVVLTAIQWIKCLALFVAPALVSIFVTNESIRQQWIWVFLIVGGGMVITNILGFFFLTDKP 469

  Fly   477 QQW 479
            .:|
Worm   470 AEW 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	102/455 (22%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	97/445 (22%)
T22F3.8	NP_504013.1	MFS	87..464	CDD:391944	89/401 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160317
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.760