DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6978 and Slc17a7

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_038966881.1	Gene:	Slc17a7 / 116638	RGDID:	620101	Length:	585	Species:	Rattus norvegicus

Alignment Length:	501	Identity:	168/501 - (33%)
Similarity:	256/501 - (51%)	Gaps:	46/501 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DSKGVSNRNRSDQEVRMERYASDGQIPRCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMVN-- 71
            |.:.|:...|....|....:.    :||    |:.:.:|...|...::.:|.|:.||||:|||
  Rat    38 DGRPVTTHTRDPPVVDCTCFG----LPR----RYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNS 94

  Fly    72 ------HTAISHTKSSTQSKE---------RDGD-----FEWSYKLQGYILSSFFYGYVITQIPF 116
                  |..:.....|...:|         :.||     |.|..:..|.|..|||:||::||||.
  Rat    95 TTHRGGHVVVQTPYRSVHKQEAVTPTVGDIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPG 159

  Fly   117 GLMIKYYGARHFLGWGMMINSLAAFFIPISAR--SGGVVGLCVVRFIQGLGEGPIVPCSHSLLAQ 179
            |.:.:.:.|....|:.::..|.....||.:||  .|.|:   .||.:|||.||...|..|.:.::
  Rat   160 GFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVI---FVRILQGLVEGVTYPACHGIWSK 221

  Fly   180 WVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFGLFSTIWCIIFICLVQE 244
            |.||.|||......:.|:..|.:|:|||:|:|..|   .||.|:||::|.|...|.:.::.:..|
  Rat   222 WAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQY---SGWSSVFYVYGSFGIFWYLFWLLVSYE 283

  Fly   245 SPAVSTRISEAERRHIMEAIWQA----QPEERSRIPFLGIAKSPPFYAILVAHAGHNYGYETLMT 305
            |||:...|||.||::|.:||.::    .|..:...|:.....|.|.|||:||:...::.:..|:.
  Rat   284 SPALHPSISEEERKYIEDAIGESAKLMNPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLI 348

  Fly   306 MLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCLIRRN-FSITVVRKLMNSLGQYGP 369
            ..|.|...|....|...|::|:||:|.|.|:..:.|.:||.|..|: .|.|.||||||..|....
  Rat   349 SQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGME 413

  Fly   370 AVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMA 434
            |..|:.||: .||..:.....:|.:|.:|....||.:||||::||:|.:|:.::|.|..|.|::.
  Rat   414 ATLLLVVGY-SHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVC 477

  Fly   435 PMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVFASG-KQQW 479
            |::.|.:...| :.|.|:.||.||:.|......||.||||| ||.|
  Rat   478 PIIVGAMTKHK-TREEWQYVFLIASLVHYGGVIFYGVFASGEKQPW 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	160/469 (34%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	154/456 (34%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	154/456 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342478
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750