DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6978 and slc17a8

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_002936892.1	Gene:	slc17a8 / 100489470	XenbaseID:	XB-GENE-988965	Length:	588	Species:	Xenopus tropicalis

Alignment Length:	507	Identity:	168/507 - (33%)
Similarity:	253/507 - (49%)	Gaps:	60/507 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DSKG-----VSNRNRSDQEVRMERYASDGQ------------------IPRCRKTRFFVVLMLFS 50
            ||.|     :..||..:..:.::   .||:                  ||:    |:.:.:|...
Frog    27 DSLGNLQRKIDGRNIEEDNIELD---EDGRPVQAPTQPPPRFDCYCCGIPK----RYIIAMMSGL 84

  Fly    51 GMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQSKERDGDFEWSYKLQGYILSSFFYGYVITQIP 115
            |...::.:|.|:.||||.|||:..:.........|   ..|.|..:..|.|..|||:||:|||||
Frog    85 GFCISFGIRCNLGVAIVEMVNNNTVYVDGKPEMQK---AQFNWDPETVGLIHGSFFWGYIITQIP 146

  Fly   116 FGLMIKYYGARHFLGWGMMINSLAAFFIPISAR--SGGVVGLCVVRFIQGLGEGPIVPCSHSLLA 178
            .|.:.....|....|..:.:.|:....||.:||  .|.|:.   ||.:|||.||...|..|.:.:
Frog   147 GGFIANKLAANRVFGAAIFLTSILNMLIPSAARVHFGCVIS---VRVLQGLVEGVTYPACHGMWS 208

  Fly   179 QWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFGLFSTIWCIIFICLVQ 243
            :|.||.|||......:.|:..|.:::|||:|:|..|   .||||:|||:|:|...|.:.::....
Frog   209 KWAPPLERSRLATTSFCGSYAGAVIAMPLAGVLVQY---IGWPSVFYIYGVFGMCWYVFWLLHAT 270

  Fly   244 ESPAVSTRISEAERRHIMEAIWQAQPEERSRIPFLGIAKSP--------PFYAILVAHAGHNYGY 300
            ||||....|:..||.:|..:|     .|.|.:...|..|:|        |.|||:||:...::.:
Frog   271 ESPAAHPSITFEERTYIETSI-----GEGSNLVTTGKFKTPWKKFFTSMPVYAIIVANFCRSWTF 330

  Fly   301 ETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCL-IRRNFSITVVRKLMNSL 364
            ..|:...|.|...|....|...|::|::|::.|.|:..|.|.|||.| .|:..|.|.|||:||..
Frog   331 YLLLISQPAYFEEVFGFPISKVGLLSAVPHMVMTIIVPVGGQLADFLRSRKILSTTTVRKIMNCG 395

  Fly   365 GQYGPAVALISVGFVHHSLWLTSVIF-ILGMGLNGAIYCGFKINHLDLSPRFAGLLISVTNCVAN 428
            |....|..|:.||:.|..  ..|:.| :|.:|.:|....||.:||||::||:|.:|:.::|.|..
Frog   396 GFGMEATLLLVVGYSHTK--AISISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGT 458

  Fly   429 LVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVFASG-KQQW 479
            |.|::.|::.|.:...| :.|.|:.||.|||.|......||.:|||| ||:|
Frog   459 LSGMVCPLIVGAMTKNK-TREEWQNVFLIAAIVHYSGVIFYGIFASGEKQEW 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	157/452 (35%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	151/439 (34%)
slc17a8	XP_002936892.1	2A0114euk	75..513	CDD:129972	159/452 (35%)
slc17a8	XP_002936892.1	MFS	81..502	CDD:119392	151/437 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010