DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and slc17a7b

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	XP_009295917.2	Gene:	slc17a7b / 100331980	ZFINID:	ZDB-GENE-131125-32	Length:	585	Species:	Danio rerio

Alignment Length:	463	Identity:	162/463 - (34%)
Similarity:	246/463 - (53%)	Gaps:	41/463 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IPRCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMV-NHTAISHTKSSTQSKERDG-------D 90
            :||    |:.:.::...|...::.:|.|:.||:|:|| |||..           |||       .
Zfish    59 LPR----RYIIAILSGLGFCISFGIRCNLGVAVVSMVNNHTVY-----------RDGKPYIVKAQ 108

  Fly    91 FEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARS--GGVV 153
            |.|..:..|.|..|||:||::||||.|.:.:.:.|....|:.::..|:....||.:||.  |.|:
Zfish   109 FSWDPETVGMIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAVVSTSILNMMIPTAARMHFGCVI 173

  Fly   154 GLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDG 218
               :||.:|||.||...|..|.:.|:|.||.|||......:.|:..|.:::|||:|:|..|   .
Zfish   174 ---LVRILQGLVEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVIAMPLAGVLVQY---S 232

  Fly   219 GWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQA----QPEERSRIPFLG 279
            ||.|:||::|.|...|.:.:|.:..||||....|:..||::|.:||.::    .|..:...|:..
Zfish   233 GWSSVFYVYGSFGVCWYLFWILVSYESPAAHPTITPEERKYIEDAIGESAGLVNPLTKFNTPWRQ 297

  Fly   280 IAKSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILA 344
            ...|.|.|||:||:...::.:..|:...|.|...|....|...||:|:||:|.|.|:..:.|.||
Zfish   298 FFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFKFEISKVGILSALPHLVMTIVVPIGGQLA 362

  Fly   345 DCLIRRNFSITV-VRKLMNSLGQYG-PAVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKIN 407
            |.|...|...|. |||||| .|.:| .|..|:.||| .|:..:.....:|.:|.:|....||.:|
Zfish   363 DYLRTHNLMTTTNVRKLMN-CGGFGLEATFLLVVGF-SHTKGVAISFLVLAVGFSGFAISGFNVN 425

  Fly   408 HLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVF 472
            |||::||:|.:|:.::|.|..|.|::.|::.|.:...| :.|.|:.||.||:.|......||.:|
Zfish   426 HLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKNK-TREEWQYVFLIASLVHYGGVIFYGLF 489

  Fly   473 ASG-KQQW 479
            ||| ||.|
Zfish   490 ASGEKQPW 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	158/456 (35%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	152/443 (34%)
slc17a7b	XP_009295917.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.650