DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6978 and slc17a6b

DIOPT Version :9

Sequence 1:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001122293.1	Gene:	slc17a6b / 100149756	ZFINID:	ZDB-GENE-030616-554	Length:	584	Species:	Danio rerio

Alignment Length:	486	Identity:	167/486 - (34%)
Similarity:	255/486 - (52%)	Gaps:	29/486 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VSNRNRSDQEVRMERYASDGQI-----PRCRKT------RFFVVLMLFSGMANAYVMRTNMSVAI 66
            :..|.:..:.:.:.......||     |.|..|      |:.:.:|...|...::.:|.|:.|||
Zfish    30 IEKRQKPGENIELTEDGRPAQINERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAI 94

  Fly    67 VAMVNHTAISHTKSSTQSKERDGDFEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGW 131
            |:|||::.| |.......||: ..|.|..:..|.|..|||:||::||||.|.:.....|....|.
Zfish    95 VSMVNNSTI-HLNGKIIIKEK-AKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANRVFGA 157

  Fly   132 GMMINSLAAFFIPISARSGGVVGLCV--VRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVY 194
            .:::.|....|||.:||  |..| ||  ||.:|||.||...|..|.:.::|.||.|||......:
Zfish   158 AILLTSTLNMFIPSAAR--GHYG-CVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSF 219

  Fly   195 AGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISEAERRH 259
            .|:..|.:::|||:|:|..|   .||.|:||::|.|...|.:.:|.:..||||....|:..||.:
Zfish   220 CGSYAGAVIAMPLAGILVQY---TGWSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEERCY 281

  Fly   260 IMEAIWQAQ----PEERSRIPFLGIAKSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIR 320
            |.|:|.::.    |.::.:.|:.....|.|.|||:||:...::.:..|:...|.|...|....|.
Zfish   282 IEESIGESAKLLGPADKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEIS 346

  Fly   321 TNGIISSLPYLAMWILAIVFGILADCLIRRN-FSITVVRKLMNSLGQYGPAVALISVGFVHHSLW 384
            ..|::|:||:|.|.|:..:.|.|||.|..:| .|.|.|||:||..|....|..|:.||: .||..
Zfish   347 KVGMLSALPHLVMTIIVPIGGQLADHLRSKNILSTTTVRKIMNCGGFGMEATLLLIVGY-SHSKG 410

  Fly   385 LTSVIFILGMGLNGAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVE 449
            :.....:|.:|.:|....||.:||||::||:|.:|:.::|.|..|.|::.|::.|.:...| :.|
Zfish   411 VAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHK-TRE 474

  Fly   450 NWRIVFYIAAGVFIFTASFYNVFASG-KQQW 479
            .|:.||.||:.|......||.:|||| ||.|
Zfish   475 EWQYVFLIASLVHYGGVIFYGIFASGEKQPW 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	160/453 (35%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	153/434 (35%)
slc17a6b	NP_001122293.1	2A0114euk	69..509	CDD:129972	161/447 (36%)
slc17a6b	NP_001122293.1	MFS	74..498	CDD:119392	153/433 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582656
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.650