DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klf15 and FZF1

DIOPT Version :9

Sequence 1:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_011260.1	Gene:	FZF1 / 852638	SGDID:	S000003223	Length:	299	Species:	Saccharomyces cerevisiae

Alignment Length:	97	Identity:	40/97 - (41%)
Similarity:	52/97 - (53%)	Gaps:	0/97 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 RGYLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKC 259
            |.|.|:|..|||:|.:|:.|:.|...|..:|||.|..|.|..:|.|...|..||.:||.:||..|
Yeast    10 RNYKCSFDGCEKVYNRPSLLQQHQNSHTNQKPYHCDEPGCGKKFIRPCHLRVHKWTHSQIKPKAC 74

  Fly   260 DYCSKCFARSDHLTKHRKVHERRLLAASRAGR 291
            ..|.|.|..:..|.:|...|||:...|||..|
Yeast    75 TLCQKRFVTNQQLRRHLNSHERKSKLASRIDR 106

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	31/78 (40%)
		C2H2 Zn finger	203..221	CDD:275368	7/17 (41%)
		C2H2 Zn finger	229..251	CDD:275368	8/21 (38%)
		zf-H2C2_2	243..268	CDD:290200	11/24 (46%)
		C2H2 Zn finger	259..279	CDD:275368	6/19 (32%)
FZF1	NP_011260.1	COG5048	15..297	CDD:227381	37/92 (40%)
		C2H2 Zn finger	17..36	CDD:275368	7/18 (39%)
		C2H2 Zn finger	44..66	CDD:275368	8/21 (38%)
		C2H2 Zn finger	74..94	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto99938
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.900