Protein Alignment Klf15 and ZNF674

DIOPT Version :9

• Sequence 1: NP_572185.1
• Gene: Klf15 / 31410
• FlyBaseID: FBgn0025679
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_001034980.1
• Gene: ZNF674 / 641339
• HGNCID: 17625
• Length: 581
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 77/314 - (24%)
• Similarity: 125/314 - (39%)
• Gaps: 91/314 - (28%)

  Fly    36 FDSTYVDTSFSGGNYNQLEFEESDYYGIITLDSNNNTNTNGNIQVGLPHV------EDPSLFID- 93
            |...:||  |:...:.||:..:.:.|..:.|::.::..:.|:: ||.|.|      .|.|...|
Human    10 FKDVFVD--FTLEEWQQLDSAQKNLYRDVMLENYSHLVSVGHL-VGKPDVIFRLGPGDESWMADG 71

  Fly    94 FNDLTVCP----PDLSDWE-QRLLDNYVEIPDL-------------------------------V 122
            ...:..|.    |::  || ...:|:|.|..|.                               .
Human    72 GTPVRTCAGEDRPEV--WEVDEQIDHYKESQDKFLWQAAFIGKETLKDESGQECKICRKIIYLNT 134

  Fly   123 DF--LPERTP------LCTDNCADFLEESNSNLRL------------------SGPPHSEIFVPD 161
            ||  :.:|.|      .|:.:..:||.::.|.:|.                  ...|....|.|:
Human   135 DFVSVKQRLPKYYSWERCSKHHLNFLGQNRSYVRKKDDGCKAYWKVCLHYNLHKAQPAERFFDPN 199

  Fly   162 RSSSSPGSSDSASPAEAVAPPSALQMSENA-AGERGYLCTFGNCEKIYAKPAHLKAHLRRHLGEK 225
            :.            .:|:....||:.|:.: .||:.|.||  .|.|::.:.|:|..|.|.|.|||
Human   200 QR------------GKALHQKQALRKSQRSQTGEKLYKCT--ECGKVFIQKANLVVHQRTHTGEK 250

  Fly   226 PYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSKCFARSDHLTKHRKVH 279
            ||.|.  :|...||:...|..|:|:|:|.|||:|..|.|.|.:...|.||::.|
Human   251 PYECC--ECAKAFSQKSTLIAHQRTHTGEKPYECSECGKTFIQKSTLIKHQRTH 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	33/78 (42%)
		C2H2 Zn finger	203..221	CDD:275368	6/17 (35%)
		C2H2 Zn finger	229..251	CDD:275368	7/21 (33%)
		zf-H2C2_2	243..268	CDD:290200	12/24 (50%)
		C2H2 Zn finger	259..279	CDD:275368	7/19 (37%)
ZNF674	NP_001034980.1	KRAB	8..68	CDD:214630	15/60 (25%)
		KRAB	8..47	CDD:279668	8/38 (21%)
		COG5048	190..580	CDD:227381	44/129 (34%)
		C2H2 Zn finger	202..218	CDD:275368	4/15 (27%)
		zf-C2H2	224..246	CDD:278523	9/23 (39%)
		C2H2 Zn finger	226..246	CDD:275368	8/21 (38%)
		zf-H2C2_2	238..263	CDD:290200	12/26 (46%)
		C2H2 Zn finger	254..274	CDD:275368	7/21 (33%)
		zf-C2H2	280..302	CDD:278523	8/21 (38%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..319	CDD:290200	4/8 (50%)
		C2H2 Zn finger	310..330	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	357..377
		C2H2 Zn finger	387..407	CDD:275368
		zf-H2C2_2	399..423	CDD:290200
		C2H2 Zn finger	415..435	CDD:275368
		zf-H2C2_2	427..450	CDD:290200
		C2H2 Zn finger	443..463	CDD:275368
		zf-H2C2_2	456..479	CDD:290200
		C2H2 Zn finger	471..491	CDD:275368
		zf-H2C2_2	484..508	CDD:290200
		C2H2 Zn finger	499..519	CDD:275368
		zf-H2C2_2	512..535	CDD:290200
		C2H2 Zn finger	527..547	CDD:275368
		zf-H2C2_2	540..563	CDD:290200
		C2H2 Zn finger	555..575	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000