DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Klf15 and klf5b

DIOPT Version :9

Sequence 1:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_688525.5	Gene:	klf5b / 560043	ZFINID:	ZDB-GENE-080424-4	Length:	344	Species:	Danio rerio

Alignment Length:	323	Identity:	100/323 - (30%)
Similarity:	134/323 - (41%)	Gaps:	100/323 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DSTYVDTSF-----SGGNYNQLE-----FEESDYYGII--TLDSNNNTN-------TNGNIQVGL 82
            |.||:.|..     |.|...:.|     |..|..:|.:  |:.....||       |..|:.:
Zfish    42 DVTYLRTGMCRTVRSVGPQIKTEPIHSSFNYSSCHGTVAPTMTHQEYTNLYTPAPETGSNVYI-- 104

  Fly    83 PHVEDPSLFIDFNDL-------------------------TVCPPDLSDWEQ------------- 109
            .| |.||  |:|.|:                         ..||| :|.:..
Zfish   105 KH-ETPS--IEFQDVPLFQLLNSDLEPNVPGGHSCTDSHNATCPP-MSTYNSIHPASSHGTERSI 165

  Fly   110 -RLLDNYVEIPDLVDFLPERTPLCTDNCADFLEESNSNLRLSGPPHSEIFVPDR-----SSSSPG 168
             .:..|...:|......|::.       |.:|..|        ||:||...|||     .:.||.
Zfish   166 CNMASNGYSLPAQFGQHPQKR-------AAYLPPS--------PPNSEPGSPDRRKELIQNLSPP 215

  Fly   169 SSDSASPAEAVA-----PPSALQMSENAA-----------GERGYLCTFGNCEKIYAKPAHLKAH 217
            .|.:||.|..:|     |..::|..:..|           ..|.:.|....|:|:|.|.:|||||
Zfish   216 PSYAASMASKMACLTPGPALSVQTQQVPAQYNRRSNPDLDKRRIHHCDVPGCKKVYTKSSHLKAH 280

  Fly   218 LRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSKCFARSDHLTKHRKVHE 280
            ||.|.|||||.|||..|.|||:|||||.||.|.|:|.||::|..||:||:|||||..|.|.|:
Zfish   281 LRTHTGEKPYKCSWEGCDWRFARSDELTRHFRKHTGAKPFQCSVCSRCFSRSDHLALHMKRHQ 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	48/78 (62%)
		C2H2 Zn finger	203..221	CDD:275368	11/17 (65%)
		C2H2 Zn finger	229..251	CDD:275368	15/21 (71%)
		zf-H2C2_2	243..268	CDD:290200	14/24 (58%)
		C2H2 Zn finger	259..279	CDD:275368	12/19 (63%)
klf5b	XP_688525.5	COG5048	236..>323	CDD:227381	40/86 (47%)
		C2H2 Zn finger	265..284	CDD:275368	11/18 (61%)
		C2H2 Zn finger	292..314	CDD:275368	15/21 (71%)
		zf-H2C2_2	306..331	CDD:290200	14/24 (58%)
		C2H2 Zn finger	322..342	CDD:275368	12/19 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4706
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.960