DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klf15 and osr2

DIOPT Version :9

Sequence 1:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_005173612.1	Gene:	osr2 / 550389	ZFINID:	ZDB-GENE-050417-183	Length:	278	Species:	Danio rerio

Alignment Length:	199	Identity:	57/199 - (28%)
Similarity:	79/199 - (39%)	Gaps:	42/199 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 IDFNDLTVCPPDLSDWEQRLLDNYVEIPDLVDF-------LPERTPLCTDNCADFLEESNSNLRL 149
            :..|..||..|.|    |.|.|  ...|..:.|       ||.:.|:...:...|   ..:||.:
Zfish    45 VQMNRWTVGFPQL----QGLAD--PRFPGALPFPAAAAHLLPHKHPVHRKDRPRF---DFANLAV 100

  Fly   150 SG----PPHSEIFVPDRSSSSPGSSDSASPAEAVAPPSALQMSENAAGERGYLCTFGNCEKIYAK 210
            :.    ||     |..:|..||    ...||....|         |..::.::|.|  |.:.:.|
Zfish   101 AATQEDPP-----VTGQSRLSP----ERRPARGRLP---------AKSKKEFICRF--CGRHFTK 145

  Fly   211 PAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSKCFARSDHLTKH 275
            ..:|..|.|.|..|:||.|.  .|...|.|.|.|..|:..||..||:||..|.|.|.:|..|..|
Zfish   146 SYNLLIHERTHTDERPYTCD--ICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVH 208

  Fly   276 RKVH 279
            :.:|
Zfish   209 KTLH 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	30/78 (38%)
		C2H2 Zn finger	203..221	CDD:275368	5/17 (29%)
		C2H2 Zn finger	229..251	CDD:275368	7/21 (33%)
		zf-H2C2_2	243..268	CDD:290200	11/24 (46%)
		C2H2 Zn finger	259..279	CDD:275368	7/19 (37%)
osr2	XP_005173612.1	COG5048	<55..>276	CDD:227381	54/189 (29%)
		C2H2 Zn finger	136..156	CDD:275368	7/21 (33%)
		zf-H2C2_2	148..173	CDD:290200	10/26 (38%)
		C2H2 Zn finger	164..184	CDD:275368	7/21 (33%)
		zf-H2C2_2	176..199	CDD:290200	10/22 (45%)
		C2H2 Zn finger	192..212	CDD:275368	7/19 (37%)
		zf-C2H2	218..240	CDD:278523
		C2H2 Zn finger	220..240	CDD:275368
		C2H2 Zn finger	248..268	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030