DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klf15 and sp2

DIOPT Version :9

Sequence 1:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_031749963.1	Gene:	sp2 / 549560	XenbaseID:	XB-GENE-968274	Length:	588	Species:	Xenopus tropicalis

Alignment Length:	181	Identity:	59/181 - (32%)
Similarity:	88/181 - (48%)	Gaps:	33/181 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 VEIPDLVDFLPERTPLCTDNCADFLEESNSNLRLSGPPHSEIFVPDRSSSSPGSSDSASPAE--- 177
            :::|..:...|.:..|...|.      |:.|:.:||...|:|    :.......|....|.|
Frog   418 MQMPVTITSTPGQPQLSVQNV------SSGNVAISGLSPSQI----QLQMEQALSGELQPGEKRR 472

  Fly   178 --AVAPPSALQMSENAAGERG---------YLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSW 231
              |...|:...      ||:|         ::|....|.:.:.|.:.|:||:|.|.||:|:||:|
Frog   473 RVACTCPNCKD------GEKGRWGPPGRKRHVCHIPECGRTFRKTSLLRAHVRLHTGERPFVCNW 531

  Fly   232 PDCVWRFSRSDELARHKRSHSGV---KPYKCDYCSKCFARSDHLTKHRKVH 279
            ..|..||:|||||.||.|:|:||   |.::|..|.|.|.||||::||.|.|
Frog   532 GFCTKRFTRSDELQRHARTHTGVTGDKRFECPQCQKRFTRSDHVSKHFKTH 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	39/81 (48%)
		C2H2 Zn finger	203..221	CDD:275368	6/17 (35%)
		C2H2 Zn finger	229..251	CDD:275368	13/21 (62%)
		zf-H2C2_2	243..268	CDD:290200	13/27 (48%)
		C2H2 Zn finger	259..279	CDD:275368	11/19 (58%)
sp2	XP_031749963.1	SP2_N	27..498	CDD:411776	18/95 (19%)
		C2H2 Zn finger	502..521	CDD:275368	6/18 (33%)
		zf-H2C2_2	514..540	CDD:404364	14/25 (56%)
		C2H2 Zn finger	529..551	CDD:275368	13/21 (62%)
		zf-H2C2_2	543..571	CDD:404364	13/27 (48%)
		C2H2 Zn finger	562..582	CDD:275368	11/19 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030