DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Klf15 and Klf14

DIOPT Version :9

Sequence 1:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001128566.1	Gene:	Klf14 / 312203	RGDID:	1306012	Length:	321	Species:	Rattus norvegicus

Alignment Length:	148	Identity:	62/148 - (41%)
Similarity:	80/148 - (54%)	Gaps:	8/148 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 DNCADFLEESNSNLRLSGPPH--SEIFVPDRSSSSPGSSDSASPAEAVAPPSALQMSENAAGERG 196
            |..:| .|.|.|...:.|.|.  .|   ||.|...|.....|.|..||.|  ..:..:.....:.
  Rat   136 DELSD-AESSCSESAILGAPEVPEE---PDDSGEVPEGPPGARPGPAVGP--TYRRRQITPASKR 194

  Fly   197 YLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDY 261
            :.|:|..|.|.|.|.:|||:|.|.|.||:|:.|.|.||..:|:||||||||.|:|:|.|.:.|..
  Rat   195 HQCSFHGCNKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSDELARHYRTHTGEKRFSCPL 259

  Fly   262 CSKCFARSDHLTKHRKVH 279
            |.|.|:||||||||.:.|
  Rat   260 CPKQFSRSDHLTKHARRH 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	44/78 (56%)
		C2H2 Zn finger	203..221	CDD:275368	9/17 (53%)
		C2H2 Zn finger	229..251	CDD:275368	14/21 (67%)
		zf-H2C2_2	243..268	CDD:290200	13/24 (54%)
		C2H2 Zn finger	259..279	CDD:275368	12/19 (63%)
Klf14	NP_001128566.1	COG5048	198..>283	CDD:227381	44/80 (55%)
		C2H2 Zn finger	200..219	CDD:275368	9/18 (50%)
		zf-H2C2_2	211..238	CDD:290200	14/26 (54%)
		C2H2 Zn finger	227..249	CDD:275368	14/21 (67%)
		zf-H2C2_2	241..266	CDD:290200	13/24 (54%)
		C2H2 Zn finger	257..277	CDD:275368	12/19 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	127	1.000	Inparanoid score	I4586
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.890