DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klf15 and Klf12

DIOPT Version :9

Sequence 1:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_038949311.1	Gene:	Klf12 / 306110	RGDID:	1309204	Length:	491	Species:	Rattus norvegicus

Alignment Length:	116	Identity:	55/116 - (47%)
Similarity:	69/116 - (59%)	Gaps:	7/116 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 SSSPGSSDSASPAEAVAPPSALQMSENAAGERGYLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYV 228
            |.||.|.:|.........|.:.:       .|.:.|.|..|.|:|.|.:|||||.|.|.|||||.
  Rat   380 SISPFSIESTRRQRRSESPDSRK-------RRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYK 437

  Fly   229 CSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSKCFARSDHLTKHRKVH 279
            |:|..|.|:|:|||||.||.|.|:||||:||..|.:.|:|||||..||:.|
  Rat   438 CTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLALHRRRH 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	47/78 (60%)
		C2H2 Zn finger	203..221	CDD:275368	10/17 (59%)
		C2H2 Zn finger	229..251	CDD:275368	13/21 (62%)
		zf-H2C2_2	243..268	CDD:290200	14/24 (58%)
		C2H2 Zn finger	259..279	CDD:275368	10/19 (53%)
Klf12	XP_038949311.1	KLF12_N	116..313	CDD:410608
		COG5048	<314..490	CDD:227381	55/116 (47%)
		C2H2 Zn finger	408..430	CDD:275368	12/21 (57%)
		C2H2 Zn finger	438..460	CDD:275368	13/21 (62%)
		zf-H2C2_2	452..477	CDD:404364	14/24 (58%)
		C2H2 Zn finger	468..488	CDD:275368	10/19 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910