DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klf15 and egr1

DIOPT Version :9

Sequence 1:NP_572185.1 Gene:Klf15 / 31410 FlyBaseID:FBgn0025679 Length:311 Species:Drosophila melanogaster
Sequence 2:NP_571323.1 Gene:egr1 / 30498 ZFINID:ZDB-GENE-980526-320 Length:511 Species:Danio rerio


Alignment Length:242 Identity:64/242 - (26%)
Similarity:96/242 - (39%) Gaps:48/242 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 SGGNYN-----QLEFEESDYYGIITLDSNNNTNTNGNIQVGLPHVEDPSLFIDFNDLTVCPPDLS 105
            ||.|::     .|::..|.|....|.          |....:|.:.|.......:::::.|||..
Zfish   196 SGPNFSTTVGTSLQYSSSTYPSAKTC----------NPSFSVPMIPDYLFTQQQSEISLVPPDQK 250

  Fly   106 DWEQRLLDNYVEIPDLVDFLPERTPLCTDNCADFLEESNSNLRLSGPPHSEIFVPDRSSSSPGSS 170
                       .|.......|..|||.|...  |..::.|. .|.....|::..|.|....|...
Zfish   251 -----------PIQTQAGQQPALTPLHTIKA--FATQTGSQ-DLKSVYQSQLIKPSRMRKYPNRP 301

  Fly   171 DSASPAEAVAPPSALQMSENAAGERGYLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCV 235
            ....|                 .||.|.|....|::.:::...|..|:|.|.|:||:.|.  .|:
Zfish   302 SKTPP-----------------HERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQCR--ICM 347

  Fly   236 WRFSRSDELARHKRSHSGVKPYKCDYCSKCFARSDHLTKHRKVHERR 282
            ..|||||.|..|.|:|:|.||:.|:.|.:.|||||...:|.|:|.|:
Zfish   348 RNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHMRQ 394

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klf15NP_572185.1 zf-C2H2_8 199..278 CDD:292531 31/78 (40%)
C2H2 Zn finger 203..221 CDD:275368 4/17 (24%)
C2H2 Zn finger 229..251 CDD:275368 10/21 (48%)
zf-H2C2_2 243..268 CDD:290200 10/24 (42%)
C2H2 Zn finger 259..279 CDD:275368 9/19 (47%)
egr1NP_571323.1 DUF3446 99..185 CDD:288757
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 133..169
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 291..312 6/37 (16%)
zf-C2H2 311..335 CDD:278523 6/23 (26%)
C2H2 Zn finger 313..335 CDD:275368 5/21 (24%)
zf-H2C2_2 327..352 CDD:290200 10/26 (38%)
C2H2 Zn finger 343..363 CDD:275368 10/21 (48%)
zf-H2C2_2 355..380 CDD:290200 10/24 (42%)
C2H2 Zn finger 371..391 CDD:275368 9/19 (47%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 384..406 4/11 (36%)
DUF3432 403..498 CDD:288743
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.030

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