DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klf15 and klf1

DIOPT Version :9

Sequence 1:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_571011.1	Gene:	klf1 / 30104	ZFINID:	ZDB-GENE-980526-55	Length:	365	Species:	Danio rerio

Alignment Length:	269	Identity:	82/269 - (30%)
Similarity:	119/269 - (44%)	Gaps:	65/269 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 EFDSTYVDTSFSGGNYNQLEFEESDYYGIITLDSNNNTNTN----------GNIQVGLPHVEDP- 88
            :|:..::|.. :..:|:|.  |....:....:.||.|.:::          |:.....|.:..|
Zfish   137 QFNCGFLDQQ-AAKSYSQA--ENPQQFSAFPVTSNVNRDSSMGKMGKSWDFGHYYQPAPLISFPD 198

  Fly    89 SLFIDFNDLT----VCPPDLSDWEQRLLDNYVEIPDLVDFLPERT-PLCTDNCADFLEESNSNLR 148
            |.|:....:|    |.||.         .:|       :|:|..: |......|:::...
Zfish   199 SKFVQTQGITMETVVFPPH---------HHY-------NFIPSYSHPRLYQQQANYVHRP----- 242

  Fly   149 LSGPPHSEIFVPDRSSSSPGSSDSASPAEAVAPPSALQMSENAAGERG--------YLCTFGNCE 205
               ||.|..  |...|..|.|:         .||:.|   |:....||        :.|.:..|:
Zfish   243 ---PPQSHF--PSTQSMVPDST---------VPPAGL---ESKRIRRGLVKRKATVHSCEYPGCQ 290

  Fly   206 KIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSKCFARSD 270
            |.|.|.:|||||||.|.|||||.|:|..|.|:|:|||||.||.|.|:|.|||:|..|.:.|:|||
Zfish   291 KTYTKSSHLKAHLRTHTGEKPYHCTWDGCGWKFARSDELTRHFRKHTGQKPYECLLCHRAFSRSD 355

  Fly   271 HLTKHRKVH 279
            ||..|.|.|
Zfish   356 HLALHMKRH 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	45/78 (58%)
		C2H2 Zn finger	203..221	CDD:275368	11/17 (65%)
		C2H2 Zn finger	229..251	CDD:275368	13/21 (62%)
		zf-H2C2_2	243..268	CDD:290200	13/24 (54%)
		C2H2 Zn finger	259..279	CDD:275368	10/19 (53%)
klf1	NP_571011.1	COG5048	287..>344	CDD:227381	35/56 (63%)
		C2H2 Zn finger	287..306	CDD:275368	11/18 (61%)
		zf-H2C2_2	298..>315	CDD:290200	13/16 (81%)
		C2H2 Zn finger	314..336	CDD:275368	13/21 (62%)
		zf-H2C2_2	328..353	CDD:290200	13/24 (54%)
		C2H2 Zn finger	344..364	CDD:275368	10/19 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910