DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klf15 and prz1

DIOPT Version :9

Sequence 1:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_593073.1	Gene:	prz1 / 2541806	PomBaseID:	SPAC4G8.13c	Length:	681	Species:	Schizosaccharomyces pombe

Alignment Length:	322	Identity:	82/322 - (25%)
Similarity:	124/322 - (38%)	Gaps:	76/322 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PLAGGDALLNIVSVGEFDSTYVDTSFSG-GNYNQLEFEESDYYGIITLDSNNNTNTNGNIQV--- 80
            |.|..:::||          |...:||| ...|.:....|......:|.:|....|:.:|..
pombe   391 PTALSNSVLN----------YDSNNFSGTPQINVVPSSPSKSQSGPSLPANPLLQTDISITYSQS 445

  Fly    81 -----GLPHVEDPSLFIDFNDLTVCPPDLS-DWEQR--------LLDNYVEIPDL-VDFLPERTP 130
                 |.|.:.:.|  .|..:..:|.|::| .:..|        ..|.|..||.| ..|......
pombe   446 ASPVSGQPAMNENS--YDLQNANLCAPEMSPTYTARHRSNSAGSRFDAYEPIPQLYTHFSHSSEC 508

  Fly   131 LCTDNCADFL-----EESNSNLRLS---GPPHSEIF------VPDRSSSSPGSSDSASPAEAVAP 181
            |..:...:.|     :.|.||..||   ..|.|...      ..:.||||...|:|.|
pombe   509 LSVNQDTELLGKIENDNSKSNDYLSVRNTRPRSRSLNSLVGNKSENSSSSKAKSESKS------- 566

  Fly   182 PSALQMSENAAGERGYLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELAR 246
                        :..|:|||..|.|.:.:..:||:|:..|...:|:.||  .|...|:|..:..|
pombe   567 ------------QGNYVCTFAGCNKRFTRAYNLKSHMNTHTNYRPFQCS--ICKKSFARQHDKRR 617

  Fly   247 HKRSHSGVKPYKCDYCSKCFARSDHLTKHRK--VHERRLLAASRAGRSLISDDLYAVRPGRK 306
            |::.|:|:|.:.|..|::.|||.|.|.:|.|  |.:..|..|:..|        ..|.|.||
pombe   618 HEQLHTGIKAFACVTCNQRFARMDALNRHYKSEVGQNCLRTATERG--------IQVPPSRK 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	29/80 (36%)
		C2H2 Zn finger	203..221	CDD:275368	5/17 (29%)
		C2H2 Zn finger	229..251	CDD:275368	7/21 (33%)
		zf-H2C2_2	243..268	CDD:290200	8/24 (33%)
		C2H2 Zn finger	259..279	CDD:275368	9/21 (43%)
prz1	NP_593073.1	COG5048	121..620	CDD:227381	62/261 (24%)
		zf-C2H2	570..594	CDD:278523	9/23 (39%)
		C2H2 Zn finger	577..594	CDD:275368	5/16 (31%)
		zf-H2C2_2	586..611	CDD:290200	9/26 (35%)
		C2H2 Zn finger	602..622	CDD:275368	7/21 (33%)
		zf-H2C2_2	616..639	CDD:290200	8/22 (36%)
		C2H2 Zn finger	630..648	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.990