DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klf15 and Klf11

DIOPT Version :9

Sequence 1:NP_572185.1 Gene:Klf15 / 31410 FlyBaseID:FBgn0025679 Length:311 Species:Drosophila melanogaster
Sequence 2:NP_848134.1 Gene:Klf11 / 194655 MGIID:2653368 Length:502 Species:Mus musculus


Alignment Length:324 Identity:98/324 - (30%)
Similarity:132/324 - (40%) Gaps:82/324 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 FATGGFQ-QLYSD--------------LEEEPLAGGDALLNIVSVGEFDSTYVDTSFSGGNYNQL 53
            |.||..| |..||              |::..||.|..:.|:||....      ...|||::   
Mouse   177 FPTGPTQEQRASDSGEGQERLLDHLEALQDTRLANGLLVTNLVSCQPC------LHKSGGSF--- 232

  Fly    54 EFEESDYYGIITLDSNNNTNTNGNIQVGLPHVEDPSLFIDFNDLTVCPPDLSDWEQRLLDNYVEI 118
                       ..|....|.....:|..||  ::|.            .|||.....|:...|..
Mouse   233 -----------PTDKGQQTGWPAAVQTCLP--KNPE------------SDLSRKITPLISVPVSS 272

  Fly   119 PDLV--------------DFLPERTPLCTDNCADFLEE--SNSNLRLSGPPHSE----IFVPDRS 163
            |.::              .||...|.|........|.:  |.|.....|||..:    :.:|..:
Mouse   273 PPVLCQMIPVAGQNGLFSAFLKPPTQLPAGTIKPILPQAASMSQPVFMGPPVPQGTVMLVLPQNT 337

  Fly   164 SSSPGSSDSASPAEA------VAP-PSALQMSENAAGE------RGYLCTFGNCEKIYAKPAHLK 215
            ...|.:..|:..|..      :|| |..|..|:|.|.:      |.|:|.|..|.|.|.|.:|||
Mouse   338 FPQPAACPSSVMAIGNTKLLPLAPAPVFLASSQNCAPQVDFSRRRNYVCNFPGCRKTYFKSSHLK 402

  Fly   216 AHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSKCFARSDHLTKHRKVH 279
            ||||.|.||||:.|||..|..:|:|||||:||:|:|:|.|.:.|..|.:.|.||||||||.:.|
Mouse   403 AHLRTHTGEKPFTCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRH 466

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klf15NP_572185.1 zf-C2H2_8 199..278 CDD:292531 45/78 (58%)
C2H2 Zn finger 203..221 CDD:275368 11/17 (65%)
C2H2 Zn finger 229..251 CDD:275368 13/21 (62%)
zf-H2C2_2 243..268 CDD:290200 11/24 (46%)
C2H2 Zn finger 259..279 CDD:275368 11/19 (58%)
Klf11NP_848134.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 133..156
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 169..194 7/16 (44%)
COG5048 382..>439 CDD:227381 33/56 (59%)
zf-C2H2 384..408 CDD:278523 14/23 (61%)
C2H2 Zn finger 389..408 CDD:275368 11/18 (61%)
zf-H2C2_2 400..427 CDD:290200 17/26 (65%)
C2H2 Zn finger 416..438 CDD:275368 13/21 (62%)
zf-H2C2_2 430..453 CDD:290200 10/22 (45%)
zf-C2H2 444..466 CDD:278523 11/21 (52%)
C2H2 Zn finger 446..466 CDD:275368 11/19 (58%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.940

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