DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klf15 and Klf3

DIOPT Version :9

Sequence 1:NP_572185.1 Gene:Klf15 / 31410 FlyBaseID:FBgn0025679 Length:311 Species:Drosophila melanogaster
Sequence 2:NP_032479.1 Gene:Klf3 / 16599 MGIID:1342773 Length:344 Species:Mus musculus


Alignment Length:213 Identity:68/213 - (31%)
Similarity:99/213 - (46%) Gaps:47/213 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 HVEDPSLF-----IDFNDLTVCPPDLSDWEQRLLDNYVEI-----PDLVDFLPERTPLCTDNCAD 138
            |::.|.:.     :|.::..:..|.:..:|:.||...::|     |...|:.||           
Mouse   159 HLQQPLMVSLSEEMDNSNSGMPVPVIESYEKPLLQKKIKIEPGIEPQRTDYYPE----------- 212

  Fly   139 FLEESNSNLRLSGPP-------HSEIFVPDRSSSSPGSSDSASPAEAVAPPSALQMSENAAGERG 196
              |.|...:....||       |..:.|      .||..           |..::..:.....|.
Mouse   213 --EMSPPLMNPVSPPQALLQENHPSVIV------QPGKR-----------PLPVESPDTQRKRRI 258

  Fly   197 YLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDY 261
            :.|.:..|.|:|.|.:|||||.|.|.|||||.|:|..|.|:|:|||||.||.|.|:|:||::|..
Mouse   259 HRCDYDGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPD 323

  Fly   262 CSKCFARSDHLTKHRKVH 279
            |.:.|:|||||..|||.|
Mouse   324 CDRSFSRSDHLALHRKRH 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klf15NP_572185.1 zf-C2H2_8 199..278 CDD:292531 44/78 (56%)
C2H2 Zn finger 203..221 CDD:275368 10/17 (59%)
C2H2 Zn finger 229..251 CDD:275368 13/21 (62%)
zf-H2C2_2 243..268 CDD:290200 12/24 (50%)
C2H2 Zn finger 259..279 CDD:275368 11/19 (58%)
Klf3NP_032479.1 Repressor domain 1..74
9aaTAD, inactive. /evidence=ECO:0000250|UniProtKB:P57682 60..68
CTBP-binding motif 61..65
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 66..111
COG5048 <169..>331 CDD:227381 57/191 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 235..254 4/35 (11%)
C2H2 Zn finger 261..283 CDD:275368 11/21 (52%)
C2H2 Zn finger 291..313 CDD:275368 13/21 (62%)
zf-H2C2_2 305..330 CDD:372612 12/24 (50%)
C2H2 Zn finger 321..341 CDD:275368 11/19 (58%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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