DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klf15 and Egr4

DIOPT Version :9

Sequence 1:NP_572185.1 Gene:Klf15 / 31410 FlyBaseID:FBgn0025679 Length:311 Species:Drosophila melanogaster
Sequence 2:NP_065621.1 Gene:Egr4 / 13656 MGIID:99252 Length:478 Species:Mus musculus


Alignment Length:344 Identity:89/344 - (25%)
Similarity:123/344 - (35%) Gaps:92/344 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 AGGDALL-----NIVSVGEFDSTYVDTSFSGGNYNQLEFE------------------------E 57
            ||.||||     ..:|...|...:.:.:.|.|..:|..||                        .
Mouse   130 AGPDALLPDLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDAAA 194

  Fly    58 SDYYG------IITLDSNNNTNTNGNIQVGLPHVEDPSLFIDFNDL--TVCPPDLSDWEQRL--- 111
            |.:.|      :::.....|..:.|:.|. .|.....::.....||  ..||.:|.....||   
Mouse   195 SAFKGPYAPWELLSAGVPGNCGSQGSFQT-TPEARFSAVGTKVEDLLSISCPAELPGPAARLYQA 258

  Fly   112 --LDNYVEIP-DLVDFLPERTPLCTDNCADFLEESNSNLRLSGPP---------------HSEIF 158
              .|.:...| ||.:.......|.|....:..........|:.||               .|:..
Mouse   259 GAYDTFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAAPPAQLSPLGLRGAATADFSKPL 323

  Fly   159 VPDRSSSSPGSSDSASPAEAVAP-PSALQMSENAAGERG----------------YLCTFGNCEK 206
            |.|    .||.|..|:|:...|. |:|   .....|.||                :.|...:|.:
Mouse   324 VAD----LPGGSGVAAPSSPAASFPAA---KARRKGRRGGKCSARCFCPRPHVKAFACPVESCVR 381

  Fly   207 IYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSKCFARSDH 271
            .:|:...|..|||.|.|.||:.|.  .|:..|||||.|..|.|:|:|.||:.||.|.:.|||||.
Mouse   382 SFARSDELNRHLRIHTGHKPFQCR--ICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDE 444

  Fly   272 LTKHRKVH-------ERRL 283
            ..:|.|||       |.||
Mouse   445 KKRHSKVHLKQKARAEERL 463

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klf15NP_572185.1 zf-C2H2_8 199..278 CDD:292531 34/78 (44%)
C2H2 Zn finger 203..221 CDD:275368 6/17 (35%)
C2H2 Zn finger 229..251 CDD:275368 10/21 (48%)
zf-H2C2_2 243..268 CDD:290200 11/24 (46%)
C2H2 Zn finger 259..279 CDD:275368 10/19 (53%)
Egr4NP_065621.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 275..302 3/26 (12%)
zf-C2H2 372..396 CDD:278523 7/23 (30%)
C2H2 Zn finger 374..396 CDD:275368 7/21 (33%)
zf-H2C2_2 388..413 CDD:290200 11/26 (42%)
COG5048 400..>458 CDD:227381 28/59 (47%)
C2H2 Zn finger 404..424 CDD:275368 10/21 (48%)
zf-H2C2_2 416..441 CDD:290200 11/24 (46%)
C2H2 Zn finger 432..452 CDD:275368 10/19 (53%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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