DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klf15 and Egr1

DIOPT Version :9

Sequence 1:NP_572185.1 Gene:Klf15 / 31410 FlyBaseID:FBgn0025679 Length:311 Species:Drosophila melanogaster
Sequence 2:NP_031939.1 Gene:Egr1 / 13653 MGIID:95295 Length:533 Species:Mus musculus


Alignment Length:231 Identity:72/231 - (31%)
Similarity:103/231 - (44%) Gaps:41/231 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 TNGNIQVGLPHVEDPSLFIDFNDLTVCPPDLSDWEQRLLDNYVEIPDLVDFLPERTPLCTDNCAD 138
            |.|..||  |.:.|........||::..||...::.  |:|..:.|.|       |||.|...  
Mouse   241 TKGGFQV--PMIPDYLFPQQQGDLSLGTPDQKPFQG--LENRTQQPSL-------TPLSTIKA-- 292

  Fly   139 FLEESNS-NLR-LSGPPHSEIFVPDRSSSSPGSSDSASPAEAVAPPSALQMSENAAGERGYLCTF 201
            |..:|.| :|: |:....|::..|.|....|.......|                 .||.|.|..
Mouse   293 FATQSGSQDLKALNTTYQSQLIKPSRMRKYPNRPSKTPP-----------------HERPYACPV 340

  Fly   202 GNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSKCF 266
            .:|::.:::...|..|:|.|.|:||:.|.  .|:..|||||.|..|.|:|:|.||:.||.|.:.|
Mouse   341 ESCDRRFSRSDELTRHIRIHTGQKPFQCR--ICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKF 403

  Fly   267 ARSDHLTKHRKVHER-------RLLAASRAGRSLIS 295
            ||||...:|.|:|.|       :.:.||.|..||.|
Mouse   404 ARSDERKRHTKIHLRQKDKKADKSVVASPAASSLSS 439

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klf15NP_572185.1 zf-C2H2_8 199..278 CDD:292531 32/78 (41%)
C2H2 Zn finger 203..221 CDD:275368 4/17 (24%)
C2H2 Zn finger 229..251 CDD:275368 10/21 (48%)
zf-H2C2_2 243..268 CDD:290200 11/24 (46%)
C2H2 Zn finger 259..279 CDD:275368 10/19 (53%)
Egr1NP_031939.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..94
DUF3446 132..207 CDD:288757
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 161..237
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 316..336 6/36 (17%)
zf-C2H2 336..360 CDD:278523 6/23 (26%)
C2H2 Zn finger 338..360 CDD:275368 5/21 (24%)
zf-H2C2_2 352..377 CDD:290200 10/26 (38%)
COG5048 363..>421 CDD:227381 28/59 (47%)
C2H2 Zn finger 368..388 CDD:275368 10/21 (48%)
zf-H2C2_2 380..405 CDD:290200 11/24 (46%)
C2H2 Zn finger 396..416 CDD:275368 10/19 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 407..478 11/33 (33%)
DUF3432 426..520 CDD:288743 6/14 (43%)
BES1_N <441..478 CDD:283367
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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