Protein Alignment Klf15 and KLF1

DIOPT Version :10

• Sequence 1: NP_572185.1
• Gene: Klf15 / 31410
• FlyBaseID: FBgn0025679
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_006554.1
• Gene: KLF1 / 10661
• HGNCID: 6345
• Length: 362
• Species: Homo sapiens
• Alignment Length: 167
• Identity: 62/167 - (37%)
• Similarity: 80/167 - (47%)
• Gaps: 41/167 - (24%)

  Fly   149 LSGPP----------HSEIFVPDRSSSSPGSSDSASPA--EAVAP-------------PSALQMS 188
            |||.|          |.::|   |....|....:.||:  ..:.|             |..:  :
Human   200 LSGYPAMYPAPQYQGHFQLF---RGLQGPAPGPATSPSFLSCLGPGTVGTGLGGTAEDPGVI--A 259

  Fly   189 ENAAGERG-----------YLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSD 242
            |.|..:||           :.|....|.|.|.|.:|||||||.|.|||||.|:|..|.|||:|||
Human   260 ETAPSKRGRRSWARKRQAAHTCAHPGCGKSYTKSSHLKAHLRTHTGEKPYACTWEGCGWRFARSD 324

  Fly   243 ELARHKRSHSGVKPYKCDYCSKCFARSDHLTKHRKVH 279
            ||.||.|.|:|.:|::|..|.:.|:|||||..|.|.|
Human   325 ELTRHYRKHTGQRPFRCQLCPRAFSRSDHLALHMKRH 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	SFP1	<193..277	CDD:227516	46/94 (49%)
		C2H2 Zn finger	203..221	CDD:275368	11/17 (65%)
		C2H2 Zn finger	229..251	CDD:275368	14/21 (67%)
		zf-H2C2_2	243..268	CDD:463886	11/24 (46%)
		C2H2 Zn finger	259..279	CDD:275368	10/19 (53%)
KLF1	NP_006554.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..110
		KLF1_N	10..279	CDD:409227	16/83 (19%)
		9aaTAD. /evidence=ECO:0000269|PubMed:31375868	71..79
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..271		5/23 (22%)
		COG5048	<281..>361	CDD:227381	45/79 (57%)
		C2H2 Zn finger	284..303	CDD:275368	11/18 (61%)
		C2H2 Zn finger	311..333	CDD:275368	14/21 (67%)
		C2H2 Zn finger	341..361	CDD:275368	10/19 (53%)