Protein Alignment Klf15 and KLF2

DIOPT Version :10

• Sequence 1: NP_572185.1
• Gene: Klf15 / 31410
• FlyBaseID: FBgn0025679
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_057354.1
• Gene: KLF2 / 10365
• HGNCID: 6347
• Length: 355
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 70/195 - (35%)
• Similarity: 92/195 - (47%)
• Gaps: 52/195 - (26%)

  Fly   126 PERTPLCTDNCADFLEESNSNLRLSGPPHSEIFVPDRSS---SSPGS---------------SDS 172
            |:..||..|..|          ||..|.....|.|....   .:||.               .|:
Human   171 PDTPPLSPDGPA----------RLPAPGPRASFPPPFGGPGFGAPGPGLHYAPPAPPAFGLFDDA 225

  Fly   173 ASPAEA--VAPPSA----------LQMSENAAGERG-----------YLCTFGNCEKIYAKPAHL 214
            |:.|.|  :|||:|          |::.| |..:||           :.|::..|.|.|.|.:||
Human   226 AAAAAALGLAPPAARGLLTPPASPLELLE-AKPKRGRRSWPRKRTATHTCSYAGCGKTYTKSSHL 289

  Fly   215 KAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSKCFARSDHLTKHRKVH 279
            |||||.|.|||||.|:|..|.|:|:|||||.||.|.|:|.:|::|..|.:.|:|||||..|.|.|
Human   290 KAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRH 354

  Fly   280  279
            Human   355  354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	SFP1	<193..277	CDD:227516	45/94 (48%)
		C2H2 Zn finger	203..221	CDD:275368	11/17 (65%)
		C2H2 Zn finger	229..251	CDD:275368	13/21 (62%)
		zf-H2C2_2	243..268	CDD:463886	11/24 (46%)
		C2H2 Zn finger	259..279	CDD:275368	10/19 (53%)
KLF2	NP_057354.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42
		KLF1_2_4_N	4..272	CDD:425360	25/111 (23%)
		9aaTAD. /evidence=ECO:0000269|PubMed:31375868	43..51
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	55..90
		Interaction with WWP1. /evidence=ECO:0000250	111..268		25/107 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..209		12/47 (26%)
		COG5048	<267..350	CDD:227381	42/82 (51%)
		C2H2 Zn finger	274..296	CDD:275368	12/21 (57%)
		C2H2 Zn finger	304..326	CDD:275368	13/21 (62%)
		C2H2 Zn finger	334..354	CDD:275368	10/19 (53%)