DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klf15 and klf15

DIOPT Version :9

Sequence 1:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_002938279.1	Gene:	klf15 / 100495857	XenbaseID:	XB-GENE-854149	Length:	394	Species:	Xenopus tropicalis

Alignment Length:	304	Identity:	104/304 - (34%)
Similarity:	145/304 - (47%)	Gaps:	62/304 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VSVGEFDSTYVDTSFSGGNYNQLE----------FEESDYYGIITLDSNNNTNTNGNIQVGLPHV 85
            :.|.||.....:|:|.....:::|          |::.|.:....|      .|.|.: ...||.
Frog   107 LKVPEFGVDMEETTFFHPTLDEIEEFLEENMKTDFKDEDRHDAKEL------RTCGQL-FSDPHA 164

  Fly    86 EDPSLFIDFNDLTV--CPPDLSDWEQRLLDNYVEIPDLVDFLPERTPLCTDNCADFLEESNSNLR 148
            .:.|:..|.|..|:  .|.|    |.....:.|.:...:..:.:..|:      :..:|||:|..
Frog   165 VNSSMKEDINGETILSVPED----ENTKGSDAVSVEGGIPVILQIQPI------EIKQESNTNQS 219

  Fly   149 LSGPPHSEI-------------FVPDRSSSSPGSSD--SASP----AEAVAPPSALQ-------- 186
            ...|.:.::             .||....||..||.  ..:|    |:.|.|...:|
Frog   220 SQFPENIKVAQLLVNIQGQTFALVPQLVQSSNLSSKFVRIAPVPIAAKPVGPGGGIQGQAGVMIG 284

  Fly   187 --MSENAAGE--RGYLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARH 247
              ..:|.|.|  :.:.|||..|.|:|.|.:|||||||||.||||:.|:||.|.|||||||||:||
Frog   285 QKFQKNPATELIKMHKCTFPGCTKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRH 349

  Fly   248 KRSHSGVKPYKCDYCSKCFARSDHLTKHRKVHERRLLAASRAGR 291
            :|||||||||:|..|.|.|||||||:||.|||  |...:||:.|
Frog   350 RRSHSGVKPYQCAVCEKKFARSDHLSKHIKVH--RFPRSSRSTR 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	56/78 (72%)
		C2H2 Zn finger	203..221	CDD:275368	11/17 (65%)
		C2H2 Zn finger	229..251	CDD:275368	16/21 (76%)
		zf-H2C2_2	243..268	CDD:290200	17/24 (71%)
		C2H2 Zn finger	259..279	CDD:275368	13/19 (68%)
klf15	XP_002938279.1	SFP1	<284..379	CDD:227516	59/94 (63%)
		C2H2 Zn finger	301..323	CDD:275368	14/21 (67%)
		C2H2 Zn finger	331..353	CDD:275368	16/21 (76%)
		zf-H2C2_2	345..370	CDD:372612	17/24 (71%)
		C2H2 Zn finger	361..381	CDD:275368	13/19 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48965
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	1	1.000	-	-		X4659
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.040