DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klf15 and egr3

DIOPT Version :9

Sequence 1:NP_572185.1 Gene:Klf15 / 31410 FlyBaseID:FBgn0025679 Length:311 Species:Drosophila melanogaster
Sequence 2:XP_002932749.1 Gene:egr3 / 100488713 XenbaseID:XB-GENE-976448 Length:380 Species:Xenopus tropicalis


Alignment Length:356 Identity:82/356 - (23%)
Similarity:129/356 - (36%) Gaps:124/356 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 GGFQQLYSDLEEEPLAGGDALLNIVSVG-EFDSTYVDTSFSG----GN----------------- 49
            ||..|.|      |:...|   |::.:| ..|....|.|::|    ||                 
 Frog    38 GGNDQHY------PVMSTD---NVIDLGLNNDKNSQDLSYNGTFQPGNKTVTYLGKFSFDSPSSW 93

  Fly    50 --YNQLEFEESDYYGIITLDSNNNTNT-----NGNIQVGLPHVEDPSLF---------------- 91
              .|.:....|...|:.|..:.|...|     ||.: :|....:..|:|                
 Frog    94 CQENIISLMSSGILGVQTSQAPNGGGTGNGGGNGGL-MGQNQNDVESMFHGLPSYAGCGDLYHEQ 157

  Fly    92 IDFNDLTVCPPDLSDWE--QRLLDN--YVEIPDLVDF-----LP--ERTPLCTDNCADFLEESNS 145
            :.|....:.|....|:.  ::.||:  :..|||...|     :|  ::.|.          ::..
 Frog   158 VGFQGGGMAPYTSQDYSSAKQSLDSGVFPMIPDYNLFHHNTEMPPVDQKPF----------QNME 212

  Fly   146 NLRLSGPPHSEIFVPDRSSSSPGSSDSASPAEAV-----------------APPSAL-------- 185
            .:|::.||                   .:|.|.:                 .||..|        
 Frog   213 AIRVNPPP-------------------ITPLETIKAFKEKQVLPSFGGMGHQPPLTLKPIRPRKY 258

  Fly   186 --QMSENAAGERGYLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHK 248
              :.|:....||.:.|....|::.:::...|..|||.|.|.||:.|.  .|:..|||||.|..|.
 Frog   259 PNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCR--ICMRSFSRSDHLTTHI 321

  Fly   249 RSHSGVKPYKCDYCSKCFARSDHLTKHRKVH 279
            |:|:|.||:.||:|.:.|||||...:|.|:|
 Frog   322 RTHTGEKPFACDFCGRKFARSDERKRHAKIH 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klf15NP_572185.1 zf-C2H2_8 199..278 CDD:292531 33/78 (42%)
C2H2 Zn finger 203..221 CDD:275368 5/17 (29%)
C2H2 Zn finger 229..251 CDD:275368 10/21 (48%)
zf-H2C2_2 243..268 CDD:290200 11/24 (46%)
C2H2 Zn finger 259..279 CDD:275368 10/19 (53%)
egr3XP_002932749.1 SFP1 <238..350 CDD:227516 39/113 (35%)
C2H2 Zn finger 274..296 CDD:275368 6/21 (29%)
COG5048 300..>352 CDD:227381 26/53 (49%)
C2H2 Zn finger 304..324 CDD:275368 10/21 (48%)
C2H2 Zn finger 332..352 CDD:275368 10/19 (53%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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