DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klf15 and egr2

DIOPT Version :9

Sequence 1:NP_572185.1 Gene:Klf15 / 31410 FlyBaseID:FBgn0025679 Length:311 Species:Drosophila melanogaster
Sequence 2:NP_001093725.1 Gene:egr2 / 100101746 XenbaseID:XB-GENE-853290 Length:429 Species:Xenopus tropicalis


Alignment Length:355 Identity:85/355 - (23%)
Similarity:132/355 - (37%) Gaps:100/355 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 GGFQQLYSDLEEEPLAGGDALLNIVSVGE-------FDSTY----------------VDTSFSGG 48
            |.|.|:.|       ..||.::::....|       :.|.|                .|..:.|.
 Frog    46 GPFDQMNS-------VTGDGMISVDMNNEKRSLDFSYSSNYPSAPRSQPLAYMGKFSFDPQYPGA 103

  Fly    49 NYNQLEFEESDYYGIITL-------DSNNNTNTNGNIQVGLPHV--------------------- 85
            .:|     ....:.|::.       .|::::.|:.|...|.|::                     
 Frog   104 GWN-----TEGIFNIVSAASILGVPPSSSSSTTSSNASSGSPNLSCSMAHPQSDMDHIYSPPPYS 163

  Fly    86 ------EDPSLFIDFNDLTVCPPDLSDWEQRLLDNYV--EIPDLVDFLPERTPLCTDNCADFLEE 142
                  :|||.||..:.....||......:...|..|  .|||.....|   |.|..:.....:.
 Frog   164 SCNEIYQDPSAFIGTSTGAPYPPPSYPSPKGASDGSVFPMIPDYSALFP---PQCQRDLHSMPDR 225

  Fly   143 SN-----SNLRLSGP--PHSEIFVPDRSSSSPGSSDSASPAEAVAPPSALQM------------- 187
            ..     .::|:..|  |.|.|    |:.:..|||:..|...:...|..|.:             
 Frog   226 KPFPCPLDSIRVPPPLTPLSTI----RNFTLGGSSNEGSRLPSAYSPHNLPLRPILRPRKYPNRP 286

  Fly   188 SENAAGERGYLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHS 252
            |:....||.|.|....|::.:::...|..|:|.|.|.||:.|.  .|:..|||||.|..|.|:|:
 Frog   287 SKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCR--ICMRNFSRSDHLTTHIRTHT 349

  Fly   253 GVKPYKCDYCSKCFARSDHLTKHRKVHERR 282
            |.||:.||||.:.|||||...:|.|:|.|:
 Frog   350 GEKPFACDYCGRKFARSDERKRHTKIHLRQ 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klf15NP_572185.1 zf-C2H2_8 199..278 CDD:292531 33/78 (42%)
C2H2 Zn finger 203..221 CDD:275368 4/17 (24%)
C2H2 Zn finger 229..251 CDD:275368 10/21 (48%)
zf-H2C2_2 243..268 CDD:290200 12/24 (50%)
C2H2 Zn finger 259..279 CDD:275368 11/19 (58%)
egr2NP_001093725.1 DUF3446 92..161 CDD:371803 9/73 (12%)
zf-C2H2 296..320 CDD:333835 6/23 (26%)
C2H2 Zn finger 298..320 CDD:275368 5/21 (24%)
COG5048 324..>391 CDD:227381 29/58 (50%)
C2H2 Zn finger 328..348 CDD:275368 10/21 (48%)
C2H2 Zn finger 356..376 CDD:275368 11/19 (58%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2698
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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