Protein Alignment Proc-R and gpr139

DIOPT Version :9

• Sequence 1: NP_001014723.1
• Gene: Proc-R / 31408
• FlyBaseID: FBgn0029723
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001352082.1
• Gene: gpr139 / 798482
• ZFINID: ZDB-GENE-050823-2
• Length: 363
• Species: Danio rerio
• Alignment Length: 473
• Identity: 93/473 - (19%)
• Similarity: 153/473 - (32%)
• Gaps: 196/473 - (41%)

  Fly    53 IGLLGNSVSIYVLTR---KRMRCTTNIYLTALAITDIAYLTCQLILSLQHYDY----PKYHFKLY 110
            :||..|.:::.:|::   :|.:.:.| ||.|||:.||..|...:.:.....|:    |..|
Zfish    38 LGLPANILTVIILSQLVLRRQKSSYN-YLLALAVADILVLLLIVFVDFLLEDFILGAPLPH---- 97

  Fly   111 WQLYGYFVWLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLLSTLS 175
             .|......|..|..:.||:|.|..||:|:||:.:||:..|....:..:|||.||...||:|::
Zfish    98 -SLNKAVQVLEFSSIHTSIWITVPLTIDRYIAVCHPLRYHTVSYPARTRKVILAVYAGCLISSV- 160

  Fly   176 TAFEHTITIGTRQIDDAYQPCNQTVANISPMPPPPVAVTPPLATPPLPTPATIWQSPDSAMESTT 240
                                                             |...|
Zfish   161 -------------------------------------------------PYYWW----------- 165

  Fly   241 SGSSNQLVDWGSGSGDGEPENIPRHRRHWQSSGFVTLPTLRKTLEEQDQKVADAAQRSGVTESLL 305
                              ||       .|..     ||               .|...|
Zfish   166 ------------------PE-------LWHG-----LP---------------GASPGG------ 179

  Fly   306 QLWRRKRSAENHNINNTDAFAFNVTEYCQNVTYYNHGLSELGYDELYSYLWNLFTLLVFVVFPLL 370
                |..||..|.:         |..:|..|                 ||           .|..
Zfish   180 ----RSSSAGQHVL---------VWVHCATV-----------------YL-----------LPCS 203

  Fly   371 LLATFNSILILLVHRSKNLRGDLTNASSIRRTKRKSNSGLKGSVSQENRVTITLIAVVLMFIVCQ 435
            :..:.|:|::      :.||            .|:|...|:|  ....:.|..|:|:..:|.|..
Zfish   204 VFFSLNAIIV------RKLR------------CRRSCFRLRG--YSTGKTTAILLAITSVFAVLW 248

  Fly   436 LPWAIYLIVNQY-----MEIQIGTQVVAGNVCNLLASLHAASNFFLYCVLSDKYRKTVRELITG- 494
            .|..:.::.:.|     |........:..:|.|:||.|:...||||||.:|.::|:....::..
Zfish   249 APRTLMILYHLYTVQPAMPGPARLLHLVTDVANMLALLNTGVNFFLYCFISKRFRRMAGTVLKAF 313

  Fly   495 YRYRRR----HARNNTSL 508
            :|.|::    :|.:|.|:
Zfish   314 FRCRKQPPPFYASHNFSI 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Proc-R	NP_001014723.1	7tm_4	52..>183	CDD:304433	40/136 (29%)
gpr139	NP_001352082.1	7tmA_GPR139	28..306	CDD:320585	88/446 (20%)
		TM helix 1	28..53	CDD:320585	4/14 (29%)
		TM helix 2	61..86	CDD:320585	9/25 (36%)
		TM helix 3	100..130	CDD:320585	11/29 (38%)
		TM helix 4	142..162	CDD:320585	8/69 (12%)
		TM helix 5	186..211	CDD:320585	8/61 (13%)
		TM helix 6	228..260	CDD:320585	6/31 (19%)
		TM helix 7	274..299	CDD:320585	11/24 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593669
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840