Protein Alignment Proc-R and SPR

DIOPT Version :9

• Sequence 1: NP_001014723.1
• Gene: Proc-R / 31408
• FlyBaseID: FBgn0029723
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001368972.1
• Gene: SPR / 31463
• FlyBaseID: FBgn0029768
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 552
• Identity: 98/552 - (17%)
• Similarity: 189/552 - (34%)
• Gaps: 224/552 - (40%)

  Fly    47 VPCVFVIGLLGNSVSIYVLTRKRMRCTTNIYLTALAITDIAYLTCQLILSLQHYDYP-KYHFK-- 108
            :|.:.:|.::.||:.:.||::|.|...||..|..:||.|:  ||.........|.|. ..|:|
  Fly    96 MPFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAICDM--LTVIFPAPGLWYMYTFGNHYKPL 158

  Fly   109 ------LYWQLYGYFV-WLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVA 166
                  |.:.::...: .:|.:   ||:::.:...::|:|.:.:....:|:||....::..|.:|
  Fly   159 HPVSMCLAYSIFNEIMPAMCHT---ISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIA 220

  Fly   167 IFCLLSTLSTAFEHTITIGTRQIDDAYQPCNQTVANISPMPPPPVAVTPPLATPPLPTPATIWQS 231
            :...|..|...|:.|           |.|.
  Fly   221 LLAFLHQLPRFFDRT-----------YMPL----------------------------------- 239

  Fly   232 PDSAMESTTSGSSNQLVDWGSGSGDGEPENIPRHRRHWQSSGFVTLPTLRKTLEEQDQKVADAAQ 296
                           :::|     :|.|..:    .|.::|
  Fly   240 ---------------VIEW-----NGSPTEV----CHLETS------------------------ 256

  Fly   297 RSGVTESLLQLWRRKRSAENHNINNTDAFAFNVTEYCQNVTYYNHGLSELGYDELYSYLWNLFTL 361
                      :|                    |.:|             :|.| ||...:.||.:
  Fly   257 ----------MW--------------------VHDY-------------IGVD-LYYTSYYLFRV 277

  Fly   362 LVFVVFPLLLLATFNSILILLVHRSKNLRGDLTNASSIRRTKRKSNSGLKGSVSQENRVTITLIA 426
            |...:.|.::|.|.|.:|...:.:::..|..|     .|..::|....|:    :.|..|:.||.
  Fly   278 LFVHLLPCIILVTLNILLFAAMRQAQERRKLL-----FRENRKKECKKLR----ETNCTTLMLIV 333

  Fly   427 VVLMFIVCQLPWAIYL-------IVNQYMEIQIGTQVVAGNVCNLLASLHAA----SNFFLYCVL 480
            ||.:|::.::|.|:..       ::.::::..:      .|:|.:|.:....    .||.:||.:
  Fly   334 VVSVFLLAEIPIAVVTAMHIVSSLIIEFLDYGL------ANICIMLTNFFLVFSYPINFGIYCGM 392

  Fly   481 SDKYRKTVRELITGYRYRRR-------------------------------------HARNNTSL 508
            |.::|:|.:|:..|....::                                     |.|::||.
  Fly   393 SRQFRETFKEIFLGRLMAKKDSSTKYSIVNGARTCTNTNETVLXXLVMLVPRRGSSDHRRSSTST 457

  Fly   509 YVPHTTTTLTQINGDHYGSN-YGGAGSRRNRN 539
                ||||.|:..|   ||. .||..|.::::
  Fly   458 ----TTTTTTKTIG---GSMIIGGEASAQHQH 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Proc-R	NP_001014723.1	7tm_4	52..>183	CDD:304433	34/140 (24%)
SPR	NP_001368972.1	7tmA_FMRFamide_R-like	90..400	CDD:410630	80/461 (17%)
		TM helix 1	92..116	CDD:410630	6/19 (32%)
		TM helix 2	124..146	CDD:410630	7/23 (30%)
		TM helix 3	169..191	CDD:410630	3/24 (13%)
		TM helix 4	214..230	CDD:410630	4/15 (27%)
		TM helix 5	270..293	CDD:410630	6/22 (27%)
		TM helix 6	328..353	CDD:410630	8/24 (33%)
		TM helix 7	368..393	CDD:410630	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467296
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D421120at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.940