Protein Alignment Proc-R and frpr-8

DIOPT Version :9

• Sequence 1: NP_001014723.1
• Gene: Proc-R / 31408
• FlyBaseID: FBgn0029723
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_509470.3
• Gene: frpr-8 / 186144
• WormBaseID: WBGene00018728
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 94/510 - (18%)
• Similarity: 171/510 - (33%)
• Gaps: 184/510 - (36%)

  Fly     3 MSSTSTATATSTATATLDE---ANATVGEMFSDADMAEVRHV---VQRILVPCVFVIGLLGNSVS 61
            |:||..:...::...|.|:   :.:|.|......:.|||.::   :..:.:|.:.|:|.....:.
 Worm     1 MNSTVISLLNNSTLVTTDQPGFSGSTKGTCSYPTNFAEVDYISTYIYLLAIPTICVLGAGAAVMC 65

  Fly    62 IYVLTRKRMRCTTNIYLTALAITDIAYLT-CQLILS------LQ-HYDYPKYHFKLYWQLYGYFV 118
            |.|.|||:||.:.|:||..|::.|:..|: ..||.|      || |.|....||  :|:...:.:
 Worm    66 IVVFTRKQMRSSLNVYLAGLSVFDLILLSFSALIFSPLQGCVLQGHGDTAVCHF--FWRSTPWTL 128

  Fly   119 WLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLLSTLSTAFEHTIT 183
            .:.:.....|::..|..|::||:|:.|||..:.:||...|..::.|:.:|.:|......||.|
 Worm   129 PISNIAQCGSVWTCVAVTVDRFLAVNYPLHSKIWCTPRRATTILIAITVFSILFKAPMFFELT-- 191

  Fly   184 IGTRQIDDAYQPCNQTVANISPMPPPPVAVTPPLATPPLPTPATIWQSPDSAMESTTSGSSNQLV 248
                 .||    |.:
 Worm   192 -----NDD----CGR-------------------------------------------------- 197

  Fly   249 DWGSGSGDGEPENIPRHRRHWQSSGFVTLPTLRKTLEEQDQKVADAAQRSGVTESLLQLWRRKRS 313
                                           ||
 Worm   198 -------------------------------LR-------------------------------- 199

  Fly   314 AENHNINNTDAFAFNVTEYCQNVTYYNHGLSELGYDELYSYLWNLFTLLVFVVFPLLLLATFNSI 378
                            |.:.::..||.......||            |:..::.|..::...|..
 Worm   200 ----------------TSFLRDNKYYKEYYVTFGY------------LIALLLIPWTVMIILNVF 236

  Fly   379 LILLVHRSKNLRGDLTNASSIRRTKRKSNSGLKGSVSQENRVTITLIAVVLMFIVCQLPWAIYLI 443
            ::..||::..:|             |....|......::.|.|:..||:||.|::..:..|:..:
 Worm   237 VVKAVHKAYKIR-------------RSMQGGKNNQEEKDRRCTLMAIAMVLTFLIFNVVAAVNNL 288

  Fly   444 VNQYMEIQIGTQVVAGNVCNLLASLHAASNFFLYCVLSDKYRKTVRELITGYRYR 498
            .....|:.:|.....|   |||..|::|||..:|.:...::|:....::.|.:.|
 Worm   289 AETVFEVSLGFWSPIG---NLLICLNSASNIVIYSLFGARFRQMCVLMLCGRQSR 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Proc-R	NP_001014723.1	7tm_4	52..>183	CDD:304433	43/138 (31%)
frpr-8	NP_509470.3	7tmA_FMRFamide_R-like	45..330	CDD:320109	82/454 (18%)
		TM helix 1	47..71	CDD:320109	5/23 (22%)
		TM helix 2	79..101	CDD:320109	8/21 (38%)
		TM helix 3	125..147	CDD:320109	2/21 (10%)
		TM helix 4	170..186	CDD:320109	3/15 (20%)
		TM helix 5	212..235	CDD:320109	4/34 (12%)
		TM helix 6	263..288	CDD:320109	8/24 (33%)
		TM helix 7	301..323	CDD:320109	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D421120at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_119272
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17098
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850