Protein Alignment Proc-R and R13H7.2

DIOPT Version :10

• Sequence 1: NP_572183.1
• Gene: Proc-R / 31408
• FlyBaseID: FBgn0029723
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001368731.1
• Gene: R13H7.2 / 177450
• WormBaseID: WBGene00020069
• Length: 459
• Species: Caenorhabditis elegans
• Alignment Length: 474
• Identity: 86/474 - (18%)
• Similarity: 163/474 - (34%)
• Gaps: 180/474 - (37%)

  Fly    42 VQRILVPCVFVIGLLGNSVSIYVLTRKRMRCTTNIYLTALAITDIAYLTCQLILSLQHYDYPKY- 105
            :.:.:.|..|..|::||.:::.||..:.||...||.|:|:||.||..|...|..||..: ||.|
 Worm    79 LNKYVFPFQFCFGVIGNVLNLCVLLSRNMRNEANILLSAMAICDIILLVTMLPNSLGVW-YPMYM 142

  Fly   106 ---HFKLYWQLYGYFVWLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAI 167
               ..|..:....:.::|.:....|:.::.:..::||::.||.|:..:.....:....:|.::.:
 Worm   143 SDWFRKFIFNSNTWTIFLANFCSCITSWLILAVSVERYMGIRSPIHFRYHWRTARVFYLIFSIIL 207

  Fly   168 FCLLSTLSTAFEH-----TITIGTRQIDDAYQPCNQTVANISPMPPPPVAVTPPLATPPLPTPAT 227
            ...|.|....||:     .|..||:..
 Worm   208 GSFLLTFFHTFEYKYGYAMIRNGTKLY-------------------------------------- 234

  Fly   228 IWQSPDSAMESTTSGSSNQLVDWGSGSGDGEPENIPRHRRHWQSSGFVTLPTLRKTLEEQDQKVA 292
                                         |.|.|:.:         .|.:||..||:.:
 Worm   235 -----------------------------GSPVNVDK---------LVDVPTWVKTMIK------ 255

  Fly   293 DAAQRSGVTESLLQLWRRKRSAENHNINNTDAFAFNVTEYCQNVTYYNHGLSELGYDELYSYLWN 357
                    |..:||
 Worm   256 --------TFKILQ--------------------------------------------------- 261

  Fly   358 LFTLLVFVVFPLLLLATFNSILILLVHRSK--NLRGDLTNASSIRRTKRKSNSGLKGSVSQENRV 420
               ::|.||.|.:.:..||.:::|::.:|:  |.|    :|.:......:..|.|:....::.:|
 Worm   262 ---VVVGVVLPTIGIFIFNMLIVLMLRKSEYFNFR----SAETKDENSNRKYSDLEIRQKRDIKV 319

  Fly   421 TITLIAVVLMFIVCQLPWAIYLIVNQY---------MEIQI-GTQVVAGNVCNLLASLHAASNFF 475
            |.|::|::..:.|..:|..|..::..:         ..|.| |:.::.|.|          :||.
 Worm   320 TFTVLAIICCYFVTHIPSVIPFVIELFNYHPDWVKVYAIPISGSWLITGKV----------ANFV 374

  Fly   476 LYCVLSDKYRKTVRELITG 494
            |:|:.|..:|:.:|:||.|
 Worm   375 LFCMSSVYFRRRLRDLIRG 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Proc-R	NP_572183.1	7tmA_FMRFamide_R-like	41..488	CDD:410630	82/466 (18%)
		TM helix 1	42..68	CDD:410630	7/25 (28%)
		TM helix 2	74..99	CDD:410630	12/24 (50%)
		TM helix 3	114..144	CDD:410630	4/29 (14%)
		TM helix 4	156..176	CDD:410630	3/19 (16%)
		TM helix 5	351..378	CDD:410630	6/26 (23%)
		TM helix 6	415..445	CDD:410630	7/29 (24%)
		TM helix 7	456..481	CDD:410630	6/24 (25%)
R13H7.2	NP_001368731.1	7tmA_FMRFamide_R-like	79..387	CDD:410630	82/466 (18%)
		TM helix 1	79..105	CDD:410630	7/25 (28%)
		TM helix 2	111..136	CDD:410630	12/24 (50%)
		TM helix 3	154..184	CDD:410630	4/29 (14%)
		TM helix 4	196..216	CDD:410630	3/19 (16%)
		TM helix 5	254..279	CDD:410630	9/92 (10%)
		TM helix 6	314..344	CDD:410630	7/29 (24%)
		TM helix 7	355..380	CDD:410630	9/34 (26%)