Protein Alignment Proc-R and CCR1

DIOPT Version :9

• Sequence 1: NP_001014723.1
• Gene: Proc-R / 31408
• FlyBaseID: FBgn0029723
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_001286.1
• Gene: CCR1 / 1230
• HGNCID: 1602
• Length: 355
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 89/520 - (17%)
• Similarity: 160/520 - (30%)
• Gaps: 224/520 - (43%)

  Fly     6 TSTATATSTATATLDEANATVGEMFSDADMAEVRHVVQRILVP---CVFVIGLLGNSVSIYVLTR 67
            |...|.....|...|..:||..:..::      |....::|.|   .||||||:||.:.:.||.:
Human     3 TPNTTEDYDTTTEFDYGDATPCQKVNE------RAFGAQLLPPLYSLVFVIGLVGNILVVLVLVQ 61

  Fly    68 -KRMRCTTNIYLTALAITDIAYLTCQLILSLQHYDYP---KYHFKLYWQLYGYFVWLCDSFGYIS 128
             ||::..|:|||..|||:|:.:|          :..|   .|..|..|........:...|.|..
Human    62 YKRLKNMTSIYLLNLAISDLLFL----------FTLPFWIDYKLKDDWVFGDAMCKILSGFYYTG 116

  Fly   129 IYIAVCF----TIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLLSTLSTAFEHTITIGTRQI 189
            :|..:.|    ||:|::||.:                    |:|.|.:       .|:|.|
Human   117 LYSEIFFIILLTIDRYLAIVH--------------------AVFALRA-------RTVTFG---- 150

  Fly   190 DDAYQPCNQTVANISPMPPPPVAVTPPLATPPLPTPATIWQSPDSAMESTTSGSSNQLVDWGSGS 254
                                            :.|...||
Human   151 --------------------------------VITSIIIW------------------------- 158

  Fly   255 GDGEPENIPRHRRHWQSSGFVTLPTLRKTLEEQDQKVADAAQRSGVTESLLQLWRRKRSAENHNI 319
                                               .:|..|...|:..|..| |
Human   159 -----------------------------------ALAILASMPGLYFSKTQ-W----------- 176

  Fly   320 NNTDAFAFNVTEYCQNVTYYNHGLSELGYDELYSYLWNLFTLLVF----VVFPLL-LLATFNSIL 379
                    ..|.:..::.:.:..|.|          |.||..|..    :|.||| ::..:..|:
Human   177 --------EFTHHTCSLHFPHESLRE----------WKLFQALKLNLFGLVLPLLVMIICYTGII 223

  Fly   380 ILLVHRSKNLRGDLTNASSIRRTKRKSNSGLKGSVSQENRVTITLIAVVLMFIVCQLPWAIYLIV 444
            .:|                :||...|.:..::           .:..::::|.:...|:.:.:::
Human   224 KIL----------------LRRPNEKKSKAVR-----------LIFVIMIIFFLFWTPYNLTILI 261

  Fly   445 NQYMEIQIGTQV-------VAGNVCNLLASLHAASNFFLYCVLSDKYRKTVRELITGYRYRRRHA 502
            :.:.:.....:.       :|..|..::|..|...|..:|..:.:::||.:|:|     :.||.|
Human   262 SVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVIYAFVGERFRKYLRQL-----FHRRVA 321

  Fly   503  502
            Human   322  321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Proc-R	NP_001014723.1	7tm_4	52..>183	CDD:304433	36/138 (26%)
CCR1	NP_001286.1	7tmA_CCR1	35..312	CDD:320311	77/466 (17%)
		TM helix 1	35..62	CDD:320311	12/26 (46%)
		TM helix 2	69..94	CDD:320311	10/34 (29%)
		TM helix 3	106..136	CDD:320311	8/29 (28%)
		TM helix 4	148..170	CDD:320311	8/117 (7%)
		TM helix 5	196..225	CDD:320311	8/28 (29%)
		TM helix 6	232..262	CDD:320311	3/40 (8%)
		TM helix 7	280..305	CDD:320311	6/24 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910