DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7024 and PDA1

DIOPT Version :9

Sequence 1:	NP_572182.1	Gene:	CG7024 / 31407	FlyBaseID:	FBgn0029722	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_011105.4	Gene:	PDA1 / 856925	SGDID:	S000000980	Length:	420	Species:	Saccharomyces cerevisiae

Alignment Length:	339	Identity:	182/339 - (53%)
Similarity:	231/339 - (68%)	Gaps:	4/339 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 ENTFKCYDLENGPTMDVELSREDALTMYTQMLELRRFETVAGNYYKERKIRGFCHLYNGQEAVAV 104
            |::|:.|.|| .|.:..|.|:...|.||..|:.:||.|......||.:||||||||..||||:||
Yeast    59 ESSFESYMLE-PPDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAV 122

  Fly   105 GMKQRLRSCDSVITAYRCHAWTYLMGVSLYEIMAELFGVRTGCSRGKGGSMHMYSDKFYGGNGIV 169
            |::..:...||:||:||||.:|::.|.|:..::|||.|.|.|.|.|||||||:|:..||||||||
Yeast   123 GIENAITKLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGGSMHLYAPGFYGGNGIV 187

  Fly   170 GAQVPLGAGIGLAHSYRKDNGVSVVLYGDGAANQGQIFESFNMAKLWCLPCIFVCENNHYGMGTH 234
            |||||||||:..||.|:.::..|..||||||:||||:||||||||||.||.:|.||||.|||||.
Yeast   188 GAQVPLGAGLAFAHQYKNEDACSFTLYGDGASNQGQVFESFNMAKLWNLPVVFCCENNKYGMGTA 252

  Fly   235 VKRASAMTEFYMRGQYIPGLWVDGNQVLAVRSATQFAVDHALK-HGPIVLEMSTYRYVGHSMSDP 298
            ..|:|||||::.||||||||.|:|..:|||..|::||.|..|. .||:|||..||||.|||||||
Yeast   253 ASRSSAMTEYFKRGQYIPGLKVNGMDILAVYQASKFAKDWCLSGKGPLVLEYETYRYGGHSMSDP 317

  Fly   299 GTSYRSREEVQSTREKRDPITSFRSQIIALCLADEEELKALDDKTRKQVDSICK--KATTDREVE 361
            ||:||:|:|:|..|.|.|||...:..:|.|.:|.|.|:||.|...||.||...:  .|....|.:
Yeast   318 GTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGIATEAEVKAYDKSARKYVDEQVELADAAPPPEAK 382

  Fly   362 LDELHTDIYAKNVD 375
            |..|..|:|.|..:
Yeast   383 LSILFEDVYVKGTE 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7024	NP_572182.1	TPP_enzymes	37..381	CDD:294952	182/339 (54%)
PDA1	NP_011105.4	TPP_enzymes	50..394	CDD:412991	181/335 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342231
Domainoid	1	1.000	342	1.000	Domainoid score	I152
eggNOG	1	0.900	-	-		E1_COG0462
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	363	1.000	Inparanoid score	I380
Isobase	1	0.950	-	0	Normalized mean entropy	S510
OMA	1	1.010	-	-		QHG54057
OrthoFinder	1	1.000	-	-		FOG0001471
OrthoInspector	1	1.000	-	-		otm46553
orthoMCL	1	0.900	-	-		OOG6_100754
Panther	1	1.100	-	-	LDO	PTHR11516
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X926
TreeFam	1	0.960	-	-
	14	13.710